ethyl (2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4-yl)carbonate

Base Information

Chemical Name:ethyl (2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4-yl)carbonate
CAS No.:1361005-25-5
Molecular Formula:C₂₆H₂₀F₃NO₅
Molecular Weight:483.444
Hs Code.:

Synonyms:ethyl (2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4-yl)carbonate

Suppliers and Price of ethyl (2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4-yl)carbonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl (2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4-yl)carbonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl (2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4-yl)carbonate

There total 4 articles about ethyl (2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4-yl)carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1354745-32-6
2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)-phenyl)quinolin-4(1H)-one

: 541-41-3
chloroformic acid ethyl ester

: 1361005-25-5
ethyl (2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4-yl)carbonate

Guidance literature:: 2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)-phenyl)quinolin-4(1H)-one; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

chloroformic acid ethyl ester; In tetrahydrofuran; for 0.5h; Inert atmosphere;
DOI:10.1021/jm201179h

Reference yield:

: 63478-10-4
2-(2'-anilinyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole

: 1361005-25-5
ethyl (2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4-yl)carbonate

Guidance literature:: Multi-step reaction with 3 steps

1.1: toluene-4-sulfonic acid / butan-1-ol / 24 h / 130 °C / Inert atmosphere

2.1: caesium carbonate; acetylacetone / 1-methyl-pyrrolidin-2-one / 48 h / 120 °C / Inert atmosphere

3.1: potassium tert-butylate / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

3.2: 0.5 h / Inert atmosphere

With potassium tert-butylate; caesium carbonate; toluene-4-sulfonic acid; acetylacetone; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; butan-1-ol;
DOI:10.1021/jm201179h

Reference yield:

: 118-48-9
isatoic anhydride

: 1361005-25-5
ethyl (2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4-yl)carbonate

Guidance literature:: Multi-step reaction with 4 steps

1.1: zinc(II) chloride / chlorobenzene / 140 °C / Inert atmosphere

2.1: toluene-4-sulfonic acid / butan-1-ol / 24 h / 130 °C / Inert atmosphere

3.1: caesium carbonate; acetylacetone / 1-methyl-pyrrolidin-2-one / 48 h / 120 °C / Inert atmosphere

4.1: potassium tert-butylate / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

4.2: 0.5 h / Inert atmosphere

With potassium tert-butylate; caesium carbonate; toluene-4-sulfonic acid; acetylacetone; zinc(II) chloride; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; chlorobenzene; butan-1-ol;
DOI:10.1021/jm201179h