Difluoroiodomethane

Base Information

• Chemical Name: Difluoroiodomethane
• CAS No.: 1493-03-4
• Molecular Formula: CHF2I
• Molecular Weight: 177.92
• Hs Code.: 2903799090
• European Community (EC) Number: 674-488-4
• DSSTox Substance ID: DTXSID90379419
• Nikkaji Number: J80.131C
• Wikidata: Q72463073
• Mol file: 1493-03-4.mol

Synonyms:Iododifluoromethane;

Chemical Property of Difluoroiodomethane

Chemical Property:

• Vapor Pressure: 841mmHg at 25°C
• Melting Point: -122 °C
• Refractive Index: 1.443
• Boiling Point: 22.1 °C at 760 mmHg
• PSA: 0.00000
• Density: 2.367g/cm³
• LogP: 1.64400
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 177.90910
• Heavy Atom Count: 4
• Complexity: 13.5

Purity/Quality:

97% ^*data from raw suppliers

Iododifluoromethane, 10 wt. % in THF ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 20
• Safety Statements: 23-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(F)(F)I

Technology Process of Difluoroiodomethane

There total 22 articles about Difluoroiodomethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(bromodifluormethyl)triphenylphosphonium bromide (58201-66-4) → bromodifluoromethane (1511-62-2) + iododifluoromethane (1493-03-4)

Guidance literature:

With water; sodium iodide; In tetrahydrofuran; at 0 ℃; for 3h;

DOI:10.1016/S0022-1139(00)82669-X

Reference yield: 80.0%

2,2-difluoro-2-(fluorosulfonyl)acetic acid (1717-59-5) → iododifluoromethane (1493-03-4)

Guidance literature:

With potassium iodide; In water; acetonitrile; at 40 ℃; for 5h;

DOI:10.1039/c39940000737

Reference yield: 80.0%

fluorosulfonyldifluoroacetyl fluoride (677-67-8) → iododifluoromethane (1493-03-4)

Guidance literature:

With sodium hydrogencarbonate; potassium iodide; In water; acetonitrile; at 30 - 40 ℃; for 0.5h;

DOI:10.1039/c39940000737

upstream raw materials:

iodoform

bromodifluoromethane

bromodifluoroacetic acid

Kalium-chlordifluoracetat

Downstream raw materials:

Carbonyl fluoride

difluoro-nitro-methane

1,1,2,2-tetrafluoroethane

N,N,1,1-Tetrafluormethylamin