1,1,2,2-Tetrafluoroethane

Base Information

• Chemical Name: 1,1,2,2-Tetrafluoroethane
• CAS No.: 359-35-3
• Molecular Formula: C2H2F4
• Molecular Weight: 102.031
• Hs Code.: 2903399090
• European Community (EC) Number: 206-628-3
• UNII: X2I96B6OVW
• DSSTox Substance ID: DTXSID60883371
• Nikkaji Number: J85.961C
• Wikidata: Q2468529
• NCI Thesaurus Code: C77540
• RXCUI: 1487139
• Mol file: 359-35-3.mol

Synonyms:1,1,2,2-TETRAFLUOROETHANE;359-35-3;Ethane, 1,1,2,2-tetrafluoro-;Freon 134;HFC-134;CHF2CHF2;UNII-X2I96B6OVW;X2I96B6OVW;EINECS 206-628-3;SCHEMBL9500;1,1,2,2-tetrafluoro-ethane;DTXSID60883371;1,1,2,2-tetrakis(fluoranyl)ethane;MFCD00042376;AKOS006228173;LS-191570;FT-0605965;R 134;Tetrafluoroethane, 1,1,2,2- (HFC 134);A823051;Q2468529

Chemical Property of 1,1,2,2-Tetrafluoroethane

Chemical Property:

• Vapor Pressure: 3920mmHg at 25°C
• Melting Point: -89 °C
• Refractive Index: 1.222
• Boiling Point: -23 °C
• PSA: 0.00000
• Density: 1.213 g/cm³
• LogP: 1.51660
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 102.00926271
• Heavy Atom Count: 6
• Complexity: 26.5

Purity/Quality:

97% ^*data from raw suppliers

1,1,2,2-Tetrafluoroethane 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Safety Statements: 23-38

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(F)F)(F)F
• General Description: 1,1,2,2-Tetrafluoroethane (TFEA) exists in two rotameric forms, anti and gauche, with the anti rotamer being more abundant in the gas phase and dominant in the crystalline phase. Vibrational spectroscopy studies, including Raman and infrared spectra, have enabled the assignment of fundamental frequencies for the anti rotamer across normal, ¹³C₂, and d₂ isotopomers, supported by isotope product rules. Assignments for the gauche rotamer remain incomplete, though estimates for missing frequencies in the normal species have been proposed. The anti rotamer's stability and prevalence are confirmed across different phases.

Technology Process of 1,1,2,2-Tetrafluoroethane

There total 45 articles about 1,1,2,2-Tetrafluoroethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Trichloroethylene (79-01-6) → carbon tetrafluoride (75-73-0) + 1,1,1,2,2-pentafluoroethane (354-33-6) + 2,2,2-trifluoroethanol (420-46-2) + 1-chloro-2,2-difluoroethane (338-65-8) + 1,1,1,2-tetrafluoroethane (811-97-2) + 1,1,1-trifluoro-2-chloroethane (75-88-7) + 1,1,2,2-tetrafluoroethane (359-35-3) + 1-chloro-2-fluoroethylene (460-16-2) + 1-Chloro-2,2-difluoroethene (359-10-4) + Hexafluoroethane (76-16-4) + Chloropentafluoroethane (76-15-3) + 1,1,1,2-tetrafluoro-2-chloroethane (2837-89-0)

Guidance literature:

Trichloroethylene; With hydrogen fluoride; chromium - based fluorination catalyst; at 180 ℃;

Cr and In on graphite catalyst; at 180 ℃; for 4h; Inconel 600 type reactor;

Cr on active alumina catalyst; Product distribution / selectivity; Inconel 600 type reactor;

Reference yield:

ethene (74-85-1) → 1,1,1,2,2-pentafluoroethane (354-33-6) + 2,2,2-trifluoroethanol (420-46-2) + 1,1,2-Trifluoroethan (430-66-0) + 1,1,1,2-tetrafluoroethane (811-97-2) + 1,1,2,2-tetrafluoroethane (359-35-3) + Hexafluoroethane (76-16-4)

Guidance literature:

With cobalt (III) fluoride; at 130 - 150 ℃; Product distribution; other hydrocarbons; var. temperatures; also CeF₄ and MnF₃ as fluorinating agent;

Reference yield:

1,1-dichlorotetrafluoroethane (374-07-2) + 1,2-dichloro-1,1,2,2-tetrafluoroethane (76-14-2) → 2,2,2-trifluoroethanol (420-46-2) + 1,1,1,2-tetrafluoroethane (811-97-2) + 1,1,2,2-tetrafluoroethane (359-35-3) + 2-chloro-1,1,2,2-tetrafluoroethane (354-25-6) + 1,1,1,2-tetrafluoro-2-chloroethane (2837-89-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; at 240 ℃; for 0.00611111h; Product distribution; Mechanism; other times, other temperatures;

DOI:10.1016/S0022-1139(00)85234-3

upstream raw materials:

1,1,2,2-tetrabromoethane

ethane

iododifluoromethane

1,1-dibromo-2,2-difluoroethane

Downstream raw materials:

1,1,1,2,2-pentafluoroethane

Hexafluoroethane

1,2-dichloro-1,1,2,2-tetrafluoroethane

methane