2-phenylethyl hydrogen 2-(phenylmethylidene)propanedioate

Base Information

• Chemical Name: 2-phenylethyl hydrogen 2-(phenylmethylidene)propanedioate
• CAS No.: 153874-60-3
• Molecular Formula: C₁₈H₁₆O₄
• Molecular Weight: 296.323
• Mol file: 153874-60-3.mol

Synonyms:2-phenylethyl hydrogen 2-(phenylmethylidene)propanedioate

Chemical Property of 2-phenylethyl hydrogen 2-(phenylmethylidene)propanedioate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-phenylethyl hydrogen 2-(phenylmethylidene)propanedioate

There total 4 articles about 2-phenylethyl hydrogen 2-(phenylmethylidene)propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 2-phenylethyl 2-(phenylmethylidene)propanedioate (153874-59-0) → 2-phenylethyl hydrogen 2-(phenylmethylidene)propanedioate (153874-60-3)

Guidance literature:

With sodium acetate; lithium bromide; In N,N-dimethyl-formamide; at 130 ℃; for 6h;

DOI:10.1002/hlca.19930760823

Reference yield:

2-phenylethanol (60-12-8) → 2-phenylethyl hydrogen 2-(phenylmethylidene)propanedioate (153874-60-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 98 percent / 18 h / 50 °C / subtilisin

2: piperidine, molecular sieves / pyridine / 2 h / 80 °C

3: LiBr, AcONa / dimethylformamide / 6 h / 130 °C

With piperidine; molecular sieve; sodium acetate; lithium bromide; In pyridine; N,N-dimethyl-formamide;

DOI:10.1002/hlca.19930760823

Reference yield:

benzaldehyde (100-52-7) → 2-phenylethyl hydrogen 2-(phenylmethylidene)propanedioate (153874-60-3)

Guidance literature:

Multi-step reaction with 2 steps

1: piperidine, molecular sieves / pyridine / 2 h / 80 °C

2: LiBr, AcONa / dimethylformamide / 6 h / 130 °C

With piperidine; molecular sieve; sodium acetate; lithium bromide; In pyridine; N,N-dimethyl-formamide;

DOI:10.1002/hlca.19930760823

upstream raw materials:

methyl 2-phenylethyl 2-(phenylmethylidene)propanedioate

2-phenylethanol

benzaldehyde

methyl 2-phenylethyl propanedioate

Downstream raw materials:

2-phenylethyl (E)-cinnamate

Refernces