1,5-Dimethoxy-2,4-dinitrobenzene

Base Information

• Chemical Name: 1,5-Dimethoxy-2,4-dinitrobenzene
• CAS No.: 1210-96-4
• Molecular Formula: C8H8N2O6
• Molecular Weight: 228.161
• Hs Code.: 2909309090
• Mol file: 1210-96-4.mol

Synonyms:2,4-Dimethoxy-1,5-dinitrobenzene;

Chemical Property of 1,5-Dimethoxy-2,4-dinitrobenzene

Chemical Property:

• Vapor Pressure: 1.43E-06mmHg at 25°C
• Refractive Index: 1.567
• Boiling Point: 410.4 °C at 760 mmHg
• Flash Point: 205.7 °C
• PSA: 110.10000
• Density: 1.416 g/cm³
• LogP: 2.56660

Purity/Quality:

99% ^*data from raw suppliers

1,5-DIMETHOXY-2,4-DINITROBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.; R5:Heating may cause an explosion.
• Hazard Codes: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.; R5:Heating may cause an explosion.
• Statements: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.; R5:Heating may cause an explosion.
• Safety Statements: S22:Do not inhale dust.; S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,5-Dimethoxy-2,4-dinitrobenzene

There total 44 articles about 1,5-Dimethoxy-2,4-dinitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2,4-dichloro-1,5-dinitrobenzene (3698-83-7) → 1,3-Dimethgxy-4,6-dinitrobenzene + 1,3-dimethoxy-4,6-dinitrobenzene (1210-96-4)

Guidance literature:

With hydrogenchloride; In methanol; water;

Reference yield: 88.0%

methanol (67-56-1) + 1,5-difluoro-2,4-dinitrobenzene (327-92-4) → 1,3-dimethoxy-4,6-dinitrobenzene (1210-96-4)

Guidance literature:

methanol; With sodium;

1,5-difluoro-2,4-dinitrobenzene; for 18h;

Reference yield: 60.0%

1-(2,4-dimethoxyphenyl)-1-(3,4-dimethoxyphenyl)-2,2-dimethylethane (89950-18-5) → 1,3-dimethoxy-4,6-dinitrobenzene (1210-96-4) + 1,3-dimethoxy-2,4,6-trinitrobenzene (1150-40-9) + 1-(4,5-dimethoxy-2-nitrophenyl)-2-methyl-1-isopropyl nitrate + 1-(2,4-dimethoxy-5-nitrophenyl)-1-(4,5-dimethoxy-2,3-dinitrophenyl)-2-methylpropane

Guidance literature:

With copper(II) nitrate; In acetic anhydride; at 40 - 50 ℃;

upstream raw materials:

methanol

1,5-difluoro-2,4-dinitrobenzene

2,4-dichloro-1,5-dinitrobenzene

sodium methylate

Downstream raw materials:

1,5-diethoxy-2,4-dinitro-benzene

4,6-dinitroresorcinol

1,3-dimethoxy-2,4,6-trinitrobenzene

1,3-diamino-4,6-dinitrobenzene

Refernces

• 1、 Wei, Xiaoxi,Zhang, Guoqing,Shen, Yi,Zhong, Yulong,Liu, Rui,Yang, Na,Al-Mkhaizim, Fayez Y.,Kline, Mark A.,He, Lan,Li, Minfeng,Lu, Zhong-Lin,Shao, Zhifeng,Gong, Bing. "Persistent Organic Nanopores Amenable to Structural and Functional Tuning". supporting information. p. 2749 - 2754. Retrieved 2016/03/12.
• 2、 -. "COMPOUNDS FOR INHIBITING CELL PROLIFERATION IN EGFR-DRIVEN CANCERS". Page/Page column 57. . Retrieved 2013/12/03.