ethyl 1-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)cyclopropanecarboxylate

Base Information

Chemical Name:ethyl 1-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)cyclopropanecarboxylate
CAS No.:1308815-03-3
Molecular Formula:C₁₆H₂₀N₂O₄
Molecular Weight:304.346
Hs Code.:

Synonyms:ethyl 1-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)cyclopropanecarboxylate

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Chemical Property of ethyl 1-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)cyclopropanecarboxylate

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Technology Process of ethyl 1-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)cyclopropanecarboxylate

There total 7 articles about ethyl 1-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)cyclopropanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1308815-01-1
ethyl 1-(4-(5-((1,3-dioxoisoindolin-2-yl)methyl)-2-oxooxazolidin-3-yl)phenyl)cyclopropanecarboxylate

: 1308815-03-3
ethyl 1-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)cyclopropanecarboxylate

Guidance literature:: With methylamine; In tetrahydrofuran; water; at 10 - 30 ℃; for 15h;

Reference yield:

: 1308814-99-4
ethyl 1-(4-aminophenyl)cyclopropanecarboxylate

: 1308815-03-3
ethyl 1-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)cyclopropanecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / 15 h / 80 °C

2: chloroform / 3 h / 65 °C

3: methylamine / water; tetrahydrofuran / 15 h / 10 - 30 °C

With methylamine; In tetrahydrofuran; ethanol; chloroform; water;

Reference yield:

: 935-44-4
1-cyano-1-phenylcyclopropane

: 1308815-03-3
ethyl 1-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)cyclopropanecarboxylate

Guidance literature:: Multi-step reaction with 6 steps

1: sodium nitrate; sulfuric acid / 0 - 20 °C

2: sulfuric acid / 10 h / 26 °C / Reflux

3: tin(II) chloride hydrate / ethyl acetate / 4 h / 25 - 75 °C

4: ethanol / 15 h / 80 °C

5: chloroform / 3 h / 65 °C

6: methylamine / water; tetrahydrofuran / 15 h / 10 - 30 °C

With sodium nitrate; tin(II) chloride hydrate; sulfuric acid; methylamine; In tetrahydrofuran; ethanol; chloroform; water; ethyl acetate;