(Dimethylaminomethylene)dimethylammonium chloride

Base Information

• Chemical Name: (Dimethylaminomethylene)dimethylammonium chloride
• CAS No.: 1071-38-1
• Molecular Formula: C5H13 N2 . Cl
• Molecular Weight: 136.625
• Hs Code.: 2923900090
• European Community (EC) Number: 626-961-1
• DSSTox Substance ID: DTXSID10430718
• Wikipedia: N,N,N%E2%80%B2,N%E2%80%B2-Tetramethylformamidinium_chloride
• Wikidata: Q28504204
• Mol file: 1071-38-1.mol

Synonyms:(Dimethylaminomethylene)dimethylammonium chloride;1071-38-1;dimethylaminomethylidene(dimethyl)azanium;chloride;N,N,N',N'-Tetramethylformamidinium chloride;[(DIMETHYLAMINO)METHYLIDENE]DIMETHYLAZANIUM CHLORIDE;SCHEMBL1231922;DTXSID10430718;BPBLGCSAYMJJJW-UHFFFAOYSA-M;(Dimethylaminomethylene)dimethylammoniumchloride,97%;J-001711;(Dimethylaminomethylene)dimethylammonium chloride, 97%;Q28504204

Chemical Property of (Dimethylaminomethylene)dimethylammonium chloride

Chemical Property:

• Melting Point: 130-139 °C(lit.)
• PSA: 6.25000
• LogP: -3.14760
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 136.0767261
• Heavy Atom Count: 8
• Complexity: 59.9

Purity/Quality:

98%,99%, ^*data from raw suppliers

(Dimethylaminomethylene)dimethylammonium chloride 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C=[N+](C)C.[Cl-]
• Uses: (Dimethylaminomethylene)dimethylammonium chloride (N,N,N′,N′-tetramethylformamidinium chloride) may be used in the synthesis of the following:aminomethylene hydantoins thiohydantoins2,2′-o-phenyl-enebis(1,3-di-meth-ylguanidine)N,N-dimethylformamide di-tert-butyl acetal

Technology Process of (Dimethylaminomethylene)dimethylammonium chloride

There total 17 articles about (Dimethylaminomethylene)dimethylammonium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) + N,N-Dimethylcarbamoyl chloride (79-44-7) → N,N,N',N'-Tetramethylformamidinium chloride (1071-38-1)

Guidance literature:

at 75 ℃; for 125h;

Reference yield: 91.0%

methyldiphenylsilane (776-76-1) + N,N,N',N'-tetramethylchlorformamidinium chloride (56043-45-9,13829-06-6) → chloromethyldiphenylsilane (144-79-6) + N,N,N',N'-Tetramethylformamidinium chloride (1071-38-1)

Guidance literature:

In acetonitrile; at 62 ℃; for 4h; Product distribution; other solvent, reaction time; other silanes;

DOI:10.1007/BF02496133

Reference yield: 90.0%

N,N-Dimethyltrimethylsilylamine (2083-91-2) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → N,N,N',N'-Tetramethylformamidinium chloride (1071-38-1)

Guidance literature:

With chloro-trimethyl-silane; In acetonitrile; at 20 ℃; for 24h;

upstream raw materials:

N,N-dimethyl-formamide

N,N-Dimethylcarbamoyl chloride

Chlorodifluoromethane

dimethyl amine

Downstream raw materials:

tris(dimethylamino)methane

butyltriphenylphosphonium chloride

<2-(Dimethylamino)-1-propylvinyl>triphenylphosphonium-chlorid

triphenyl-propylsulfanylmethyl-phosphonium; chloride

Refernces

• 1、 Sheludyakov,Belyakova,Shevchenko,Chernyshev. "Synthesis and properties of novel dialkylaminocarbenium salts". . p. 997 - 1002. Retrieved 1997.
• 2、 Barth, Emily L.,Charboneau, David J.,Germe, Cameron C.,Hazari, Nilay,Huang, Haotian,Mercado, Brandon Q.,Uehling, Mycah R.,Zultanski, Susan L.. "Tunable and Practical Homogeneous Organic Reductants for Cross-Electrophile Coupling". . p. 21024 - 21036. Retrieved 2021/12/14.
• 3、 -. "CYTOMEGALOVIRUS INHIBITOR COMPOUNDS". Page/Page column 51; 52. . Retrieved 2013/10/22.