1-(Methylsulfonyl)-2-phenyldiazene

Base Information

• Chemical Name: 1-(Methylsulfonyl)-2-phenyldiazene
• CAS No.: 23265-32-9
• Molecular Formula: C7H8 N2 O2 S
• Molecular Weight: 184.219
• DSSTox Substance ID: DTXSID90559810
• Mol file: 23265-32-9.mol

Synonyms:1-(Methylsulfonyl)-2-phenyldiazene;23265-32-9;N-phenyliminomethanesulfonamide;Diazene, 1-(methylsulfonyl)-2-phenyl-;1086226-01-8;DTXSID90559810;AKOS006280808;N-(PHENYLIMINO)METHANESULFONAMIDE;(E)-1-(Methanesulfonyl)-2-phenyldiazene;G24593;EN300-26192256

Chemical Property of 1-(Methylsulfonyl)-2-phenyldiazene

Chemical Property:

• PSA: 67.24000
• LogP: 2.81070
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 184.03064868
• Heavy Atom Count: 12
• Complexity: 247

Purity/Quality:

1-(Methylsulfonyl)-2-phenyldiazene 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CS(=O)(=O)N=NC1=CC=CC=C1

Technology Process of 1-(Methylsulfonyl)-2-phenyldiazene

There total 7 articles about 1-(Methylsulfonyl)-2-phenyldiazene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

sodium methansulfinate (20277-69-4) + aniline (62-53-3) → 1-(methylsulfonyl)-2-(phenyl)diazene (23265-32-9)

Guidance literature:

aniline; With tetrafluoroboric acid; In water; for 0.25h;

With sodium nitrite; In water; at 0 ℃; for 1h;

sodium methansulfinate; In 1,2-dichloro-ethane; at 0 ℃; for 8h;

Reference yield: 70.0%

methanesulfonyl chloride (124-63-0) + phenylhydrazine (100-63-0) → 1-(methylsulfonyl)-2-(phenyl)diazene (23265-32-9)

Guidance literature:

With copper(ll) sulfate pentahydrate; potassium carbonate; In dichloromethane; at 20 ℃;

DOI:10.1039/c5nj01760b

Reference yield: 70.0%

furan (110-00-9) + 1-(methylsulfonyl)-2-(4-cyanophenyl)diazene → 1-(methylsulfonyl)-2-(phenyl)diazene (23265-32-9)

Guidance literature:

In water; acetonitrile; for 15h; Inert atmosphere; Irradiation;

DOI:10.1021/acs.joc.6b01619

upstream raw materials:

methylsulfinic acid

benzene diazonium chloride

sodium methansulfinate

benzenediazonium tetrafluoroborate

Downstream raw materials:

4-benzylbiphenyl

(methylsulfonyl)diphenylmethane

2-benzyl-1,1'-biphenyl

4-phenylazobenzene

Refernces

• 1、 -. "Process for converting substituted arylamine into arylazomethyl sulfone". Paragraph 0052-0057. . Retrieved 2021/06/26.
• 2、 -. "SUBSTITUTED SULFONYL HYDRAZIDES AS INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY". Paragraph 0241. . Retrieved 2020/01/24.