(3-chloromethyl-4-methoxy-phenyl)-[6-(2-methoxy-phenyl)-pyrimidin-4-yl]-ammonium chloride

Base Information

Chemical Name:(3-chloromethyl-4-methoxy-phenyl)-[6-(2-methoxy-phenyl)-pyrimidin-4-yl]-ammonium chloride
CAS No.:1569986-42-0
Molecular Formula:C₁₉H₁₈ClN₃O₂*ClH
Molecular Weight:392.285
Hs Code.:

Synonyms:(3-chloromethyl-4-methoxy-phenyl)-[6-(2-methoxy-phenyl)-pyrimidin-4-yl]-ammonium chloride

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Chemical Property of (3-chloromethyl-4-methoxy-phenyl)-[6-(2-methoxy-phenyl)-pyrimidin-4-yl]-ammonium chloride

Chemical Property:

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Technology Process of (3-chloromethyl-4-methoxy-phenyl)-[6-(2-methoxy-phenyl)-pyrimidin-4-yl]-ammonium chloride

There total 8 articles about (3-chloromethyl-4-methoxy-phenyl)-[6-(2-methoxy-phenyl)-pyrimidin-4-yl]-ammonium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1569982-45-1
(2-methoxy-5-(6-(2-methoxyphenyl)pyrimidin-4-ylamino)phenyl)methanol

: 1569986-42-0
(3-chloromethyl-4-methoxy-phenyl)-[6-(2-methoxy-phenyl)-pyrimidin-4-yl]-ammonium chloride

Guidance literature:: With phosphorus trichloride; In dichloromethane; N,N-dimethyl-formamide; at 0 - 20 ℃;

Reference yield:

: 75634-03-6
4-chloro-6-(2-methoxy-phenyl)-pyrimidine

: 1569986-42-0
(3-chloromethyl-4-methoxy-phenyl)-[6-(2-methoxy-phenyl)-pyrimidin-4-yl]-ammonium chloride

Guidance literature:: Multi-step reaction with 3 steps

1: tert-butyl alcohol / 6 h / Reflux

2: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C

3: phosphorus trichloride / N,N-dimethyl-formamide; dichloromethane / 0 - 20 °C

With lithium aluminium tetrahydride; phosphorus trichloride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; tert-butyl alcohol;

Reference yield:

: 1569986-04-4
(4-methoxy-3-methoxycarbonyl-phenyl)-[6-(2-methoxy-phenyl)-pyrimidin-4-yl]-ammonium chloride

: 1569986-42-0
(3-chloromethyl-4-methoxy-phenyl)-[6-(2-methoxy-phenyl)-pyrimidin-4-yl]-ammonium chloride

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C

2: phosphorus trichloride / N,N-dimethyl-formamide; dichloromethane / 0 - 20 °C

With lithium aluminium tetrahydride; phosphorus trichloride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;