(R)-N-<1-(3,5-dimethoxyphenyl)-2-propylidene>-α-methylbenzenemethanamine

Base Information

• Chemical Name: (R)-N-<1-(3,5-dimethoxyphenyl)-2-propylidene>-α-methylbenzenemethanamine
• CAS No.: 183256-23-7
• Molecular Formula: C₁₉H₂₃NO₂
• Molecular Weight: 297.397
• Mol file: 183256-23-7.mol

Synonyms:(R)-N-<1-(3,5-dimethoxyphenyl)-2-propylidene>-α-methylbenzenemethanamine

Chemical Property of (R)-N-<1-(3,5-dimethoxyphenyl)-2-propylidene>-α-methylbenzenemethanamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-N-<1-(3,5-dimethoxyphenyl)-2-propylidene>-α-methylbenzenemethanamine

There total 3 articles about (R)-N-<1-(3,5-dimethoxyphenyl)-2-propylidene>-α-methylbenzenemethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3,5-dimethoxyphenyl)acetone (18917-77-6) + (R)-1-phenyl-ethyl-amine (3886-69-9) → (R)-N-<1-(3,5-dimethoxyphenyl)-2-propylidene>-α-methylbenzenemethanamine (183256-23-7)

Guidance literature:

In toluene; for 96h; Heating;

Reference yield:

3,5-dimethoxybenzaldehdye (7311-34-4) → (R)-N-<1-(3,5-dimethoxyphenyl)-2-propylidene>-α-methylbenzenemethanamine (183256-23-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 62 percent / NH₄OAc / 16 h / 100 °C

2: 90 percent / Fe, glacial AcOH / 3 h / Heating

3: toluene / 16 h / 110 °C

With ammonium acetate; iron; acetic acid; In toluene;

DOI:10.1002/jhet.5570330460

Reference yield:

1,3-dimethoxy-5-(2-nitroprop-1-en-1-yl)benzene (18917-76-5) → (R)-N-<1-(3,5-dimethoxyphenyl)-2-propylidene>-α-methylbenzenemethanamine (183256-23-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / Fe, glacial AcOH / 3 h / Heating

2: toluene / 16 h / 110 °C

With iron; acetic acid; In toluene;

DOI:10.1002/jhet.5570330460

upstream raw materials:

(3,5-dimethoxyphenyl)acetone

(R)-1-phenyl-ethyl-amine

3,5-dimethoxybenzaldehdye

1,3-dimethoxy-5-(2-nitroprop-1-en-1-yl)benzene

Downstream raw materials:

(R,R)-N-<1-(3,5-dimethoxyphenyl)-2-propyl>-α-methylbenzenemethanamine

N-[(R)-2-(3-Hydroxy-5-methoxy-phenyl)-1-methyl-ethyl]-acetamide

(R)-N-<1-(3,5-dimethoxyphenyl)-2-propyl>acetamide

(R)-3,5-dimethoxy-α-methylbenzeneethanamine hydrochloride