18917-77-6

Basic information

• Product Name: (3,5-DIMETHOXYPHENYL)ACETONE
• Synonyms: (3,5-DIMETHOXYPHENYL)ACETONE;1-(3,5-DiMethoxyphenyl)acetone;1-(3,5-dimethoxyphenyl)propan-2-one
• CAS NO: 18917-77-6
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.23
• Product Categories: Aromatic Ketones (substituted)
• Mol File: 18917-77-6.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3,5-DIMETHOXYPHENYL)ACETONE(CAS DataBase Reference)
• NIST Chemistry Reference: (3,5-DIMETHOXYPHENYL)ACETONE(18917-77-6)
• EPA Substance Registry System: (3,5-DIMETHOXYPHENYL)ACETONE(18917-77-6)

Safety Data

• Hazardous Substances Data: 18917-77-6(Hazardous Substances Data)

Usage

General Description

"(3,5-DIMETHOXYPHENYL)ACETONE," also known as 1-(3,5-dimethoxyphenyl)ethanone, is a chemical compound with the molecular formula C11H14O3. It consists of a phenyl ring with two methoxy (CH3O) groups attached at the 3 and 5 positions, and a ketone group attached to the first carbon of the phenyl ring. (3,5-DIMETHOXYPHENYL)ACETONE is commonly used in organic synthesis and pharmaceutical manufacturing due to its versatile reactivity and potential applications. It is also used as a building block in the synthesis of various bioactive compounds, and as a flavoring agent in the food and beverage industry. Additionally, it has been studied for its potential pharmacological activities, such as anti-inflammatory and antioxidant effects. Overall, (3,5-DIMETHOXYPHENYL)ACETONE is a valuable chemical compound with a range of potential uses in various industries.

Upstream product

• 25245-27-6 1-iodo-3,5-dimethoxybenzene 
• 67-64-1 acetone 
• 13388-75-5 3,5-dimethoxyphenylacetonitrile 
• 74-88-4 methyl iodide 
• 99-96-7 4-hydroxy-benzoic acid 
• 75-16-1 methylmagnesium bromide 
• 195001-43-5 2-(3,5-dimethoxyphenyl)-N-methoxy-N-methylacetamide 
• 7051-16-3 1-chloro-3,5-dimethoxybenzene 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 4670-10-4 (3,5-dimethoxyphenyl)acetic acid 
• 15601-07-7 2-(3,5-dimethoxyphenyl)acetyl chloride 
• 15681-48-8 dimethyllithium cuprate 
• 18917-76-5 1,3-dimethoxy-5-(2-nitroprop-1-en-1-yl)benzene 
• 64-17-5 ethanol 

Downstream Products

• 128350-29-8 3-((S)-2-Benzylamino-propyl)-5-methoxy-phenol 
• 104371-22-4 (2S)-1-(3',5'-dimethoxyphenyl)-2-aminopropane 
• 177971-34-5 (1R)-2-(3,5-dimethoxyphenyl)-1-methylethylamine 
• 183256-23-7 (R)-N-<1-(3,5-dimethoxyphenyl)-2-propylidene>-α-methylbenzenemethanamine 
• 4670-10-4 (3,5-dimethoxyphenyl)acetic acid 
• 79859-93-1 1-(3,5-dimethoxyphenyl)propan-2-ol 
• 18917-78-7 3-(3,5-dimethoxy-phenyl)-butan-2-one 
• 170753-26-1 4-(3',5'-dimethoxyphenyl)-4-methyl-3-vinylcyclohex-2-enone 
• 195001-62-8 6-(3',5'-dimethoxyphenyl)-3-methoxy-6-methylcyclohex-2-enone 
• 250212-49-8 (R,R)-N-<1-(3,5-dimethoxyphenyl)-2-propyl>-α-methylbenzenemethanamine 
• 34489-36-6 1,1-dimethyl-(3',5'-dimethoxyphenyl)ethanol 
• 1206790-98-8 (2R)-N-(2''-methyl-4'',5''-dimethoxy-8''-naphthyl)-N-acetyl-1-(3',5'-dimethoxyphenyl)-2-aminopropane 
• 1206475-97-9 (2R)-N-(2''-methyl-4'',5''-dimethoxy-8''-naphthyl)-1-(3',5'-dimethoxyphenyl)-2-aminopropane 
• 1206475-86-6 2S-N-(2''-methyl-4'',5''-dimethoxy-8''naphthyl)-1-(3',5'-dimethoxyphenyl)-2-aminopropane 

Relevant articles and documents

Identification and Quantification of a Phytotoxic Metabolite from Alternaria dauci

Alternaria dauci is the causal agent of Alternaria leaf blight (ALB) in carrot (Daucus carota) crops around the world. However, to date, A. dauci has received limited attention in its production of phytotoxic metabolites. In this investigation, the bioassay-guided isolation of the extract from liquid cultures of A. dauci resulted in the isolation of two metabolites identified as α-acetylorcinol (1) and p-hydroxybenzoic acid (2), based on their spectroscopic data and results from chemical correlation reactions. Testing of both metabolites in different assays showed an important phytotoxic activity for p-hydroxybenzoic acid (2) when tested in the leaf-spot assay on parsley (Petroselinum crispum), in the leaf infiltration assay on tobacco (Nicotiana alata) and marigold (Tagetes erecta), and in the immersion assay on parsley and parsnip (Pastinaca sativa) leaves. Quantification of the two metabolites in the crude extract of A. dauci kept at different times showed that p-hydroxybenzoic acid (2) is one of the first metabolites to be synthesized by the pathogen, suggesting that this salicylic acid derivative could play an important role in the pathogenicity of the fungus.

Direct Asymmetric Reductive Amination for the Synthesis of Chiral β-Arylamines

The highly efficient and direct asymmetric reductive amination of arylacetones catalyzed by an iridium complex for the preparation of enantiomerically pure β-arylamines is described. The monodentate phosphoramidite ligand exhibits superb reactivity (TONs of up to 20 000) and enantioselectivity (up to 99 % ee). Additives played important roles in this reductive coupling reaction. Asymmetric reductive coupling of a ketone and an amine is a straightforward and atom-economic approach for preparing optically enriched amines. The highly efficient and direct asymmetric reductive amination of arylacetones, catalyzed by an iridium complex, supplies enantiomerically pure β-arylamines. The new phosphoramidite ligands reported show superb reactivity and enantioselectivity in this reductive coupling. M.S.=molecular sieves, TFA=trifluoroacetic acid.

Synthesis of carbocyclic analogs of dehydroaltenusin: Identification of a stable inhibitor of calf DNA polymerase α

Syntheses of carbocyclic analogs of dehydroaltenusin tautomers are reported. Both target compounds, cDHA (2,8-dihydroxy-6-methoxy-10a-methyl-10,10a-dihydrophenanthrene-3,9-dione) and cDHAs (4′,5-dihydroxy-6′-methoxy-2-methylspiro[cyclohexa[2,5]diene-1,1′-