N-benzyl-N'-(4-methoxyphenyl)cyanamide

Base Information

• Chemical Name: N-benzyl-N'-(4-methoxyphenyl)cyanamide
• CAS No.: 1449512-40-6
• Molecular Formula: C₁₅H₁₄N₂O
• Molecular Weight: 238.289
• Mol file: 1449512-40-6.mol

Synonyms:N-benzyl-N'-(4-methoxyphenyl)cyanamide

Chemical Property of N-benzyl-N'-(4-methoxyphenyl)cyanamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of N-benzyl-N'-(4-methoxyphenyl)cyanamide

There total 15 articles about N-benzyl-N'-(4-methoxyphenyl)cyanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

N-(4-methoxyphenyl)cyanamide (13519-16-9) + benzyl bromide (100-39-0) → N-benzyl-N'-(4-methoxyphenyl)cyanamide (1449512-40-6)

Guidance literature:

With potassium carbonate; In ethanol; at 25 ℃; for 3h; Sonication; Green chemistry;

DOI:10.1016/j.ultsonch.2019.04.038

Reference yield: 82.0%

N-cyano-N-(4-methoxyphenyl)-4-methylbenzenesulfonamide + benzyl alcohol (100-51-6,185532-71-2) → N-benzyl-N'-(4-methoxyphenyl)cyanamide (1449512-40-6)

Guidance literature:

benzyl alcohol; With tetra-(n-butyl)ammonium iodide; sodium tert-pentoxide; In tetrahydrofuran; at 25 ℃; Sealed tube; Inert atmosphere;

N-cyano-N-(4-methoxyphenyl)-4-methylbenzenesulfonamide; In tetrahydrofuran; at 25 ℃; for 16h; Sealed tube; Inert atmosphere;

DOI:10.1021/acs.orglett.7b01710

Reference yield: 70.0%

trimethylsilyl cyanide (7677-24-9) + benzyl(4-methoxyphenyl)amine (17377-95-6) → N-benzyl-N'-(4-methoxyphenyl)cyanamide (1449512-40-6)

Guidance literature:

With sodium hypochlorite; In acetonitrile; at 23 ℃; for 4h; Reagent/catalyst; Inert atmosphere;

DOI:10.1021/ol403245r

upstream raw materials:

4-methoxyformanilide

benzyl bromide

4-methoxyphenyl isoselenocyanate

p-methoxyphenylisonitrile