Z-DL-ALA-GLY-OH

Base Information

• Chemical Name: Z-DL-ALA-GLY-OH
• CAS No.: 2503-31-3
• Molecular Formula: C13H16 N2 O5
• Molecular Weight: 280.28
• Hs Code.: 2924297099
• Mol file: 2503-31-3.mol

Synonyms:Glycine,N-(N-carboxy-DL-alanyl)-, N-benzyl ester (6CI,7CI,8CI); Glycine,N-[N-[(phenylmethoxy)carbonyl]-DL-alanyl]-; Glycine,N-[N-[(phenylmethoxy)carbonyl]alanyl]-

Chemical Property of Z-DL-ALA-GLY-OH

Chemical Property:

• PSA: 104.73000
• LogP: 1.28390
• Storage Temp.: -15°C

Purity/Quality:

98%Min ^*data from raw suppliers

Z-DL-Ala-Gly-OH 99+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Z-DL-ALA-GLY-OH

There total 29 articles about Z-DL-ALA-GLY-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

N,O-bis(trimethylsilyl)glycine (7364-42-3) + N-Cbz-Ala (1142-20-7) → N-benzyloxycarbonyl-L-alanylglycine (2503-31-3,3235-17-4,34286-66-3)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 ℃; Inert atmosphere;

DOI:10.1021/jo2024703

Reference yield: 89.0%

3-(N-benzyloxycarbonyl-L-alanyl)-1,3-thiazolidine-2-thione (76413-56-4) + glycine (56-40-6,18875-39-3,25718-94-9) → N-benzyloxycarbonyl-L-alanylglycine (2503-31-3,3235-17-4,34286-66-3)

Guidance literature:

With triethylamine; In tetrahydrofuran; water; for 0.0166667h; Ambient temperature; other 3-acyl-1,3-thiazolidine-2-thione;

DOI:10.1246/cl.1981.463

Reference yield: 80.0%

Z-L-Ala-Gly-OMe (4840-29-3) → N-benzyloxycarbonyl-L-alanylglycine (2503-31-3,3235-17-4,34286-66-3)

Guidance literature:

With sodium hydroxide; In water; acetone; at 20 ℃; for 0.75h;

DOI:10.1021/acs.jmedchem.9b00823

upstream raw materials:

ethyl N-(benzyloxycarbonyl)-L-alanylglycinate

Z-L-Ala-Gly-OMe

Benzyloxycarbonyl-L-alaninphenylthiolester

glycine

Downstream raw materials:

S-benzyl-N-{N-[N-(N-benzyloxycarbonyl-L-alanyl)-glycyl]-L-valyl}-L-cysteine benzyl ester

alanylglycine

Z-Ala-Gly-Boc Hydrazid

N²-(Benzyloxycarbonyl)-N¹-(methoxymethyl)-L-alaninamid