(ISOPROPYLTHIO)ACETIC ACID

Base Information

• Chemical Name: (ISOPROPYLTHIO)ACETIC ACID
• CAS No.: 22818-59-3
• Molecular Formula: C5H10 O2 S
• Molecular Weight: 134.199
• Hs Code.: 2930909090
• Mol file: 22818-59-3.mol

Synonyms:Aceticacid, (isopropylthio)- (6CI,8CI); Acetic acid, [(1-methylethyl)thio]- (9CI);Carboxymethyl isopropyl sulfide; Isopropylthioacetic acid

Chemical Property of (ISOPROPYLTHIO)ACETIC ACID

Chemical Property:

• Vapor Pressure: 0.0272mmHg at 25°C
• Refractive Index: 1.49
• Boiling Point: 227.9°C at 760 mmHg
• PKA: 3.87±0.10(Predicted)
• Flash Point: 91.6°C
• PSA: 62.60000
• Density: 1.117g/cm³
• LogP: 1.21260

Purity/Quality:

98%Min ^*data from raw suppliers

(isopropylthio)aceticacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (ISOPROPYLTHIO)ACETIC ACID

There total 7 articles about (ISOPROPYLTHIO)ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

mercaptoacetic acid (68-11-1) + isopropyl bromide (75-26-3) → (isopropylthio)acetic acid (22818-59-3)

Guidance literature:

With sodium hydroxide; In methanol; water; at 20 - 40 ℃; for 20.5h;

Reference yield:

chloroacetic acid (79-11-8) → (isopropylthio)acetic acid (22818-59-3)

Guidance literature:

DOI:10.1021/ja01178a030

Reference yield:

isopropyl bromide (75-26-3) → (isopropylthio)acetic acid (22818-59-3)

Guidance literature:

With methanol;

upstream raw materials:

mercaptoacetic acid

chloroacetic acid

2-iodo-propane

isopropyl carbamimidothioate hydrobromide

Downstream raw materials:

(propane-2-sulfinyl)-acetic acid

2-(isopropylsulfonyl)acetic acid

Ph₃Bi(OOCCH₂S(i-C₃H₇))2

triethylamine hydrobromide