1R-trans-methyl caronaldehydate

Base Information

• Chemical Name: 1R-trans-methyl caronaldehydate
• CAS No.: 27335-33-7
• Molecular Formula: C8H12O3
• Molecular Weight: 156.181
• Hs Code.: 2918300090
• Mol file: 27335-33-7.mol

Synonyms:1R-trans-methyl caronaldehydate

Chemical Property of 1R-trans-methyl caronaldehydate

Chemical Property:

• Boiling Point: 186.8±33.0 °C(Predicted)
• PSA: 43.37000
• Density: 1.149±0.06 g/cm3(Predicted)
• LogP: 0.63050

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1R-trans-methyl caronaldehydate

There total 25 articles about 1R-trans-methyl caronaldehydate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + (1R,4R,5S)-4-hydroxy-6,6-dimethyl-3-oxabicyclo[3.1.0]hexa-2-one (26771-21-1) → methyl (+/-)-cis-3-formyl-2,2-dimethyl-1-cyclopropanecarboxylate (26770-99-0,27335-33-7,27335-34-8,41301-44-4,51424-62-5,55701-02-5,62138-41-4,67968-42-7,84710-48-5)

Guidance literature:

In diethyl ether; ethyl acetate; at -10 ℃; for 1h;

Reference yield: 89.0%

(1R,3S)-3-Chlorocarbonyl-2,2-dimethyl-cyclopropanecarboxylic acid methyl ester (76842-28-9,120591-67-5) → methyl (+/-)-cis-3-formyl-2,2-dimethyl-1-cyclopropanecarboxylate (26770-99-0,27335-33-7,27335-34-8,41301-44-4,51424-62-5,55701-02-5,62138-41-4,67968-42-7,84710-48-5)

Guidance literature:

With hydrogen; sodium acetate; palladium on activated charcoal; In acetone; for 0.666667h; under 1241.2 Torr; Ambient temperature;

Reference yield: 61.0%

(1S,3R)-3-(1,2-Dihydroxy-2-methyl-propyl)-2,2-dimethyl-cyclopropanecarboxylic acid methyl ester → methyl (+/-)-cis-3-formyl-2,2-dimethyl-1-cyclopropanecarboxylate (26770-99-0,27335-33-7,27335-34-8,41301-44-4,51424-62-5,55701-02-5,62138-41-4,67968-42-7,84710-48-5)

Guidance literature:

With sodium periodate; phosphate buffer; In methanol; at 20 ℃; for 1h;

DOI:10.1016/S0040-4039(02)01270-4

upstream raw materials:

(1S,3R)-2,2-Dimethyl-3-((1E,3E)-penta-1,3-dienyl)-cyclopropanecarboxylic acid methyl ester

(1R,3S)-3-Chlorocarbonyl-2,2-dimethyl-cyclopropanecarboxylic acid methyl ester

diazomethane

(1R,4R,5S)-4-hydroxy-6,6-dimethyl-3-oxabicyclo[3.1.0]hexa-2-one

Downstream raw materials:

4-methoxymethyl-2,3,5,6-tetrafluorobenzyl (1R)-trans-3-[(1Z)-2-cyano-1,3-butadienyl]-2,2-dimethylcyclopropane carboxylate

(1R,3R)-2,2-Dimethyl-3-((E)-2-methyl-3-oxoprop-1-en-1-yl)cyclopropane-1-carboxylic Acid

Pyrethrin II

jasmolin II

Refernces

• 1、 Farina, F.,Martin, M. V.,Soria, M. L.. "PSEUDOESTERES Y DERIVADOS XXXIII. SINTESIS DE COMPUESTOS CICLOPROPANICOS POR FOTOLISIS DE PIRAZOLINAS OBTENIDAS POR CICLOADICION 1,3-DIPOLAR A LA 5-METOXI-2(5H)-FURANONA". . p. 65 - 73. Retrieved 2007/10/02.
• 2、 Muljiani, Z.,Gadre, Smita,Joshi, Vijaya,Mitra, R. B.. "A SIMPLE PROCESS FOR THE SYNTHESIS OF METHYL (+/-)-CIS-3-FORMYL-2,2-DIMETHYL-1-CYCLOPROPANECARBOXYLATE". . p. 135 - 140. Retrieved 2007/10/02.