5-{[2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]methyl}-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione

Base Information

• Chemical Name: 5-{[2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]methyl}-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
• CAS No.: 1029062-63-2
• Molecular Formula: C₁₈H₁₇N₅OS
• Molecular Weight: 351.432

Synonyms:5-{[2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]methyl}-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione

Chemical Property of 5-{[2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]methyl}-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-{[2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]methyl}-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione

There total 6 articles about 5-{[2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]methyl}-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

2-{[2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]acetyl}-N-methylhydrazinecarbothioamide (1029062-45-0) → 5-{[2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]methyl}-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (1029062-63-2)

Guidance literature:

With sodium hydroxide; for 1h; Reflux;

DOI:10.1016/j.ejmech.2019.04.012

Reference yield:

4-methoxy-benzaldehyde (123-11-5) → 5-{[2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]methyl}-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (1029062-63-2)

Guidance literature:

Multi-step reaction with 5 steps

1: sodium metabisulfite

2: potassium hydroxide / dimethyl sulfoxide

3: hydrazine hydrate / ethanol

4: ethanol / 3 h / Reflux

5: sodium hydroxide / 1 h / Reflux

With sodium metabisulfite; hydrazine hydrate; potassium hydroxide; sodium hydroxide; In ethanol; dimethyl sulfoxide;

DOI:10.1016/j.ejmech.2019.04.012

Reference yield:

1,2-diamino-benzene (95-54-5) → 5-{[2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]methyl}-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (1029062-63-2)

Guidance literature:

Multi-step reaction with 5 steps

1: sodium metabisulfite

2: potassium hydroxide / dimethyl sulfoxide

3: hydrazine hydrate / ethanol

4: ethanol / 3 h / Reflux

5: sodium hydroxide / 1 h / Reflux

With sodium metabisulfite; hydrazine hydrate; potassium hydroxide; sodium hydroxide; In ethanol; dimethyl sulfoxide;

DOI:10.1016/j.ejmech.2019.04.012

upstream raw materials:

2-{[2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]acetyl}-N-methylhydrazinecarbothioamide

4-methoxy-benzaldehyde

1,2-diamino-benzene

2-(4-methoxyphenyl)-1H-benzimidazole

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1029062-63-2 5-{[2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]methyl}-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione

Send

Send

Metric Ton KG G Pound L ML

Send

Send