4,5-Dichloro-2,8-dimethylquinoline

Base Information

Chemical Name:4,5-Dichloro-2,8-dimethylquinoline
CAS No.:21629-52-7
Molecular Formula:C₁₁H₉Cl₂N
Molecular Weight:226.105
Hs Code.:2933499090
DSSTox Substance ID:DTXSID80586453
Wikidata:Q82478594
Mol file:21629-52-7.mol

Synonyms:4,5-Dichloro-2,8-dimethylquinoline;21629-52-7;4,5-dichloro-2,8-dimethyl-quinoline;SCHEMBL9730943;DTXSID80586453;CPOIUXDRGLGBNU-UHFFFAOYSA-N;MFCD00272341;AKOS002673960;AB05621;DB-066579

Suppliers and Price of 4,5-Dichloro-2,8-dimethylquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 4,5-Dichloro-2,8-dimethylquinoline

Chemical Property:

Vapor Pressure:0.000645mmHg at 25°C
Refractive Index:1.629
Boiling Point:319.1°Cat760mmHg
PKA:3.32±0.50(Predicted)
Flash Point:176.3°C
PSA：12.89000
Density:1.305g/cm³
LogP:4.15840
XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:225.0112047
Heavy Atom Count:14
Complexity:210

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=C(C=C1)Cl)C(=CC(=N2)C)Cl

Technology Process of 4,5-Dichloro-2,8-dimethylquinoline

There total 4 articles about 4,5-Dichloro-2,8-dimethylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 216876-32-3
C₁₃H₁₆ClNO₂

: 21629-52-7
4,5-dichloro-2,8-dimethyl-quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: diphenylether / 0.5 h / Reflux

2: trichlorophosphate / 3 h / Reflux

With trichlorophosphate; In diphenylether;
DOI:10.1007/s00044-011-9854-3

Reference yield:

: 95-79-4
5-chloro-2-methyl-benzenamine

: 21629-52-7
4,5-dichloro-2,8-dimethyl-quinoline

Guidance literature:: Multi-step reaction with 3 steps

1: methanol / 7 h / 40 °C

2: diphenylether / 0.5 h / Reflux

3: trichlorophosphate / 3 h / Reflux

With trichlorophosphate; In methanol; diphenylether;
DOI:10.1007/s00044-011-9854-3