Welcome to LookChem.com Sign In|Join Free

CAS

  • or

21629-50-5

Post Buying Request

21629-50-5 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

21629-50-5 Usage

General Description

5-CHLORO-2,8-DIMETHYL-4-QUINOLINOL, also known as nitroxoline, is a synthetic antibacterial and antifungal agent that is primarily used to treat urinary tract infections. It is classified as a quinolone antibiotic and works by inhibiting the growth of bacteria and fungi in the urinary tract. The compound has a broad spectrum of activity against various pathogens, including Escherichia coli, Staphylococcus aureus, and Candida species. Its chemical structure consists of a quinoline ring with a chlorine atom at the 5-position and methyl groups at the 2- and 8-positions. Nitroxoline is available in oral formulations and is generally well-tolerated, with common side effects including gastrointestinal upset and skin reactions. Due to its effectiveness and low resistance development, nitroxoline remains a valuable option for the treatment of urinary tract infections.

Check Digit Verification of cas no

The CAS Registry Mumber 21629-50-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,6,2 and 9 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 21629-50:
(7*2)+(6*1)+(5*6)+(4*2)+(3*9)+(2*5)+(1*0)=95
95 % 10 = 5
So 21629-50-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H10ClNO/c1-6-3-4-8(12)10-9(14)5-7(2)13-11(6)10/h3-5H,1-2H3,(H,13,14)

21629-50-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-chloro-2,8-dimethyl-1H-quinolin-4-one

1.2 Other means of identification

Product number -
Other names F3284-7418

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:21629-50-5 SDS

21629-50-5Relevant articles and documents

N1-{4-[(10S)-Dihydroartemisinin-10-oxyl]}phenylmethylene-N 2-(2-methylquinoline-4-yl)hydrazine derivatives as antiplasmodial falcipain-2 inhibitors

Luo, Wei,Liu, Yang,Wang, Jian,Guo, Chun,Lu, Wei-Qiang,Cui, Kun-Qiang

, p. 3073 - 3079,7 (2020/08/20)

A series of N1-{4-[(10S)-dihydroartemisinin- 10-oxyl]}phenylmethylene-N2-(2-methylquinoline-4-yl) hydrazine derivatives 9a-9n possessing 4-quinolylhydrazone and artemisinin cores were herein synthesized and evaluated for their activities against cysteine protease falcipain- 2 of Plasmodium falciparum. The structures were clearly confirmed by elemental analysis, 1H NMR, and mass spectra. The pharmacological results indicated that all compounds showed excellent activity against recombinant falcipain-2 (IC50 = 0.15-2.28 μM). The best one of this series was compound 9d (IC50 = 0.15 μM). The molecular docking results showed that the compound 9d made close contact with the key active site of cysteine protease falcipain-2.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 21629-50-5