2-styrylpyrrole

Base Information

• Chemical Name: 2-styrylpyrrole
• CAS No.: 35563-07-6
• Molecular Formula: C₁₂H₁₁N
• Molecular Weight: 169.226
• Mol file: 35563-07-6.mol

Synonyms:2-styrylpyrrole

Chemical Property of 2-styrylpyrrole

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-styrylpyrrole

There total 28 articles about 2-styrylpyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-pyrrole aldehyde (1003-29-8,254729-95-8) + benzyl alcohol (100-51-6,185532-71-2) → 2-((E)-2-phenylethen-1-yl)pyrrole (35563-07-6)

Guidance literature:

benzyl alcohol; With triethylphosphine hydrobromide; at 100 ℃; for 8h; under 3750.38 - 5250.53 Torr; Inert atmosphere; Neat (no solvent);

With water; sodium hydroxide; for 0.0833333h; Inert atmosphere; Sonication;

2-pyrrole aldehyde; In water; at 100 ℃; for 0.416667h; under 3750.38 - 5250.53 Torr; optical yield given as %de; chemoselective reaction; Inert atmosphere; Microwave irradiation;

DOI:10.1002/chem.201000438

Reference yield: 88.0%

2-phenylpyrrolo[1,2-b]isothiazole-5-carbonitrile 1,1-dioxide + sodium ethanolate (141-52-6) → (Z)-ethyl 2-(4-cyano-1H-pyrrol-2-yl)-1-phenylethenesulfonate + 2-((E)-2-phenylethen-1-yl)pyrrole (35563-07-6)

Guidance literature:

In tetrahydrofuran; ethanol; at 20 ℃; Sealed tube;

DOI:10.1021/acs.joc.7b01340

Reference yield: 79.0%

C17H19NO2 → 2-styrylpyrrole (35563-07-6)

Guidance literature:

With sodium ethanolate; In tetrahydrofuran; methanol; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1016/j.tetlet.2019.03.051

upstream raw materials:

2-phenyl-1-pyrrol-2-yl-ethanol

2-pyrrole aldehyde

benzyl(triphenyl)phosphonium bromide

benzyltriphenylphosphonium bromide

Downstream raw materials:

cis-2-styrylpyrrole

2-formyl-5-((E)-2-phenylethen-1-yl)pyrrole

(Z)-methyl 3-methoxy-2-[(E)-2-styrylpyrrol-1-yl]acrylate