C₁₄H₁₇NO₃

Base Information

• Chemical Name: C₁₄H₁₇NO₃
• CAS No.: 1421663-96-8
• Molecular Formula: C₁₄H₁₇NO₃
• Molecular Weight: 247.294
• Mol file: 1421663-96-8.mol

Synonyms:C₁₄H₁₇NO₃

Chemical Property of C₁₄H₁₇NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₇NO₃

There total 3 articles about C₁₄H₁₇NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl 2-cyano-3-(4-methoxyphenyl)pentanedioate → C14H17NO3 (1421663-96-8)

Guidance literature:

With sodium chloride; In water; dimethyl sulfoxide; at 180 ℃; for 2.5h; Inert atmosphere;

DOI:10.1139/cjc-2012-0340

Reference yield:

ethyl 2-cyano-3-(4-methoxyphenyl)prop-2-enoate (2286-29-5) → C14H17NO3 (1421663-96-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: lithium diisopropyl amide / hexane; tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

1.2: 2 h / 0 °C / Inert atmosphere

2.1: sodium chloride / water; dimethyl sulfoxide / 2.5 h / 180 °C / Inert atmosphere

With sodium chloride; lithium diisopropyl amide; In tetrahydrofuran; hexane; water; dimethyl sulfoxide;

DOI:10.1139/cjc-2012-0340

Reference yield:

4-methoxy-benzaldehyde (123-11-5) → C14H17NO3 (1421663-96-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: acetic acid; ammonium acetate / toluene / 2 h / Dean-Stark; Inert atmosphere; Reflux

2.1: lithium diisopropyl amide / hexane; tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

2.2: 2 h / 0 °C / Inert atmosphere

3.1: sodium chloride / water; dimethyl sulfoxide / 2.5 h / 180 °C / Inert atmosphere

With ammonium acetate; acetic acid; sodium chloride; lithium diisopropyl amide; In tetrahydrofuran; hexane; water; dimethyl sulfoxide; toluene;

DOI:10.1139/cjc-2012-0340

upstream raw materials:

4-methoxy-benzaldehyde

ethyl 2-cyano-3-(4-methoxyphenyl)prop-2-enoate

Downstream raw materials:

C₂₄H₄₇NO₄SSi₂

C₂₉H₅₅NO₆SSi₂

(1E)-N-[1-[[[5-(1,1-dimethylethyl)dimethylsilyl]oxy]-3-[[4-(1,1-dimethylethyl)dimethylsilyl]-oxy]-phenyl]pentyl]-1,3-butadiene-1-sulfonamide

C₁₂H₁₅NO₂