N-(3-chlorophenyl)-5-(4-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide

Base Information

Chemical Name:N-(3-chlorophenyl)-5-(4-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide
CAS No.:1257421-84-3
Molecular Formula:C₁₄H₉Cl₂N₃O₂S₂
Molecular Weight:386.282
Hs Code.:

Synonyms:N-(3-chlorophenyl)-5-(4-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide

Suppliers and Price of N-(3-chlorophenyl)-5-(4-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of N-(3-chlorophenyl)-5-(4-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of N-(3-chlorophenyl)-5-(4-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide

There total 6 articles about N-(3-chlorophenyl)-5-(4-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 108-42-9
3-chloro-aniline

: 328527-98-6
5-(4-chlorophenyl)-1,3,4-thiadiazole-2-sulfonyl chloride

: 1257421-84-3
N-(3-chlorophenyl)-5-(4-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide

Guidance literature:: With triethylamine; In acetonitrile; at 20 ℃; for 6h;
DOI:10.3390/molecules15129046

Reference yield:

: 1126-46-1
Methyl 4-chlorobenzoate

: 1257421-84-3
N-(3-chlorophenyl)-5-(4-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide

Guidance literature:: Multi-step reaction with 5 steps

1: hydrazine hydrate / ethanol / 8 h / Reflux

2: potassium hydroxide / ethanol / 20 °C

3: sulfuric acid / -2 - 0 °C

4: hydrogenchloride; water; chlorine / 1,2-dichloro-ethane / -2 °C

5: triethylamine / acetonitrile / 6 h / 20 °C

With hydrogenchloride; sulfuric acid; water; chlorine; hydrazine hydrate; triethylamine; potassium hydroxide; In ethanol; 1,2-dichloro-ethane; acetonitrile;
DOI:10.3390/molecules15129046

Reference yield:

: 38539-88-7
potassium p-chlorobenzoylhydrazinodithioformate

: 1257421-84-3
N-(3-chlorophenyl)-5-(4-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid / -2 - 0 °C

2: hydrogenchloride; water; chlorine / 1,2-dichloro-ethane / -2 °C

3: triethylamine / acetonitrile / 6 h / 20 °C

With hydrogenchloride; sulfuric acid; water; chlorine; triethylamine; In 1,2-dichloro-ethane; acetonitrile;
DOI:10.3390/molecules15129046