C₂₄H₂₆N₆O₄

Base Information

• Chemical Name: C₂₄H₂₆N₆O₄
• CAS No.: 1346242-95-2
• Molecular Formula: C₂₄H₂₆N₆O₄
• Molecular Weight: 462.508
• Mol file: 1346242-95-2.mol

Synonyms:C₂₄H₂₆N₆O₄

Chemical Property of C₂₄H₂₆N₆O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₂₆N₆O₄

There total 12 articles about C₂₄H₂₆N₆O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

C23H25N5O5S (1346245-10-0) + methylamine (74-89-5) → C23H26N6O2 (1346242-96-3) + C24H26N6O4 (1346242-95-2)

Guidance literature:

With potassium carbonate; In ethanol; acetonitrile; at 80 ℃; sealed vessel;

Reference yield:

7-bromo-1H-quinoxalin-2-one (82031-32-1) → C23H26N6O2 (1346242-96-3) + C24H26N6O4 (1346242-95-2)

Guidance literature:

Multi-step reaction with 7 steps

1.1: trichlorophosphate / 2 h / 100 °C

1.2: Cooling with ice

2.1: sodium carbonate / triphenylphosphine; palladium diacetate / 1,2-dimethoxyethane; water / 4 h / Reflux

3.1: sodium t-butanolate / palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / 1,4-dioxane / 90 °C / Inert atmosphere

4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 5 °C / Inert atmosphere

4.2: 5 - 20 °C / Inert atmosphere

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 5 h / 20 °C

5.2: Cooling with ice

6.1: triethylamine / dichloromethane / 2 h / 5 - 20 °C / Inert atmosphere

7.1: potassium carbonate / acetonitrile; ethanol / 80 °C / sealed vessel

With tetrabutyl ammonium fluoride; sodium hydride; sodium carbonate; potassium carbonate; triethylamine; sodium t-butanolate; trichlorophosphate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane; 1,2-dimethoxyethane; ethanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; mineral oil;

Reference yield:

7-bromo-2-chloroquinoxaline (89891-65-6) → C23H26N6O2 (1346242-96-3) + C24H26N6O4 (1346242-95-2)

Guidance literature:

Multi-step reaction with 6 steps

1.1: sodium carbonate / triphenylphosphine; palladium diacetate / 1,2-dimethoxyethane; water / 4 h / Reflux

2.1: sodium t-butanolate / palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / 1,4-dioxane / 90 °C / Inert atmosphere

3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 5 °C / Inert atmosphere

3.2: 5 - 20 °C / Inert atmosphere

4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 5 h / 20 °C

4.2: Cooling with ice

5.1: triethylamine / dichloromethane / 2 h / 5 - 20 °C / Inert atmosphere

6.1: potassium carbonate / acetonitrile; ethanol / 80 °C / sealed vessel

With tetrabutyl ammonium fluoride; sodium hydride; sodium carbonate; potassium carbonate; triethylamine; sodium t-butanolate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane; 1,2-dimethoxyethane; ethanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; mineral oil;

upstream raw materials:

3.5-dimethoxyaniline

C₂₃H₂₅N₅O₅S

methylamine

7-bromo-1H-quinoxalin-2-one