2,4-DIMETHYL-3-FLUOROBENZOIC ACID METHYL ESTER

Base Information

• Chemical Name: 2,4-DIMETHYL-3-FLUOROBENZOIC ACID METHYL ESTER
• CAS No.: 26584-27-0
• Molecular Formula: C₁₀H₁₁FO₂
• Molecular Weight: 182.195
• Hs Code.: 2916399090
• Mol file: 26584-27-0.mol

Synonyms:2,4-DIMETHYL-3-FLUOROBENZOIC ACID METHYL ESTER;3-FLUORO-2,4-DIMETHYL-BENZOIC ACID METHYL ESTER;METHYL 2,4-DIMETHYL-3-FLUOROBENZOATE

Chemical Property of 2,4-DIMETHYL-3-FLUOROBENZOIC ACID METHYL ESTER

Chemical Property:

• Boiling Point: 234.6±28.0 °C(Predicted)
• PSA: 26.30000
• Density: 1 +-.0.06 g/cm3(Predicted)
• LogP: 2.22910

Purity/Quality:

98%Min ^*data from raw suppliers

SG000459:2,4-Dimethyl-3-fluorobenzoicacidmethylester 98 ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-DIMETHYL-3-FLUOROBENZOIC ACID METHYL ESTER

There total 3 articles about 2,4-DIMETHYL-3-FLUOROBENZOIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Brom-2-fluor-1.3-dimethylbenzol (26584-26-9) → Methyl-3-fluor-2,4-dimethylbenzoat (26584-27-0)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) Mg, THF, (ii) /BRN= 1900390/

2: (i) SOCl₂, (ii) /BRN= 1098229/

DOI:10.1021/jo00836a010

Reference yield:

3-bromo-2,6-dimethyl-aniline (53874-26-3) → Methyl-3-fluor-2,4-dimethylbenzoat (26584-27-0)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) NaNO₂, aq. H₂SO₄, (ii) HBF₄

2: (i) Mg, THF, (ii) /BRN= 1900390/

3: (i) SOCl₂, (ii) /BRN= 1098229/

DOI:10.1021/jo00836a010

Reference yield:

methanol (67-56-1) + 3-fluoro-2,4-dimethylbenzoic acid (26583-81-3) → Methyl-3-fluor-2,4-dimethylbenzoat (26584-27-0)

Guidance literature:

Multistep reaction; (i) SOCl₂, (ii) /BRN= 1098229/;

DOI:10.1021/jo00836a010

upstream raw materials:

methanol

3-fluoro-2,4-dimethylbenzoic acid

4-Brom-2-fluor-1.3-dimethylbenzol

3-bromo-2,6-dimethyl-aniline

Downstream raw materials:

3-Fluoro-1,2,4-trimethylbenzene

6-Brom-3-fluor-1.2.4-trimethylbenzol

3-Fluor-2.4-dimethylbenzylchlorid

Methyl-4-fluor-2,3,5-trimethylbenzoat