2',4'-dibenzoyloxyacetophenone ethylene hemithioketal

Base Information

• Chemical Name: 2',4'-dibenzoyloxyacetophenone ethylene hemithioketal
• CAS No.: 136257-98-2
• Molecular Formula: C₂₄H₂₀O₅S
• Molecular Weight: 420.486
• Mol file: 136257-98-2.mol

Synonyms:2',4'-dibenzoyloxyacetophenone ethylene hemithioketal

Chemical Property of 2',4'-dibenzoyloxyacetophenone ethylene hemithioketal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2',4'-dibenzoyloxyacetophenone ethylene hemithioketal

There total 3 articles about 2',4'-dibenzoyloxyacetophenone ethylene hemithioketal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2,4-dibenzoyloxyacetophenone (66832-97-1) + 2-hydroxyethanethiol (60-24-2) → 2',4'-dibenzoyloxyacetophenone ethylene hemithioketal (136257-98-2)

Guidance literature:

With boron trifluoride diethyl etherate; In diethyl ether; chloroform; for 4h; Heating;

DOI:10.1016/S0040-4020(01)80960-1

Reference yield:

2',4'-dihydroxy-4-acetophenone (89-84-9) → 2',4'-dibenzoyloxyacetophenone ethylene hemithioketal (136257-98-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 62 percent / pyridine / 6 h

2: 92 percent / BF₃*OEt₂ / diethyl ether; CHCl₃ / 4 h / Heating

With pyridine; boron trifluoride diethyl etherate; In diethyl ether; chloroform;

DOI:10.1016/S0040-4020(01)80960-1

Reference yield:

benzoyl chloride (98-88-4) → 2',4'-dibenzoyloxyacetophenone ethylene hemithioketal (136257-98-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 62 percent / pyridine / 6 h

2: 92 percent / BF₃*OEt₂ / diethyl ether; CHCl₃ / 4 h / Heating

With pyridine; boron trifluoride diethyl etherate; In diethyl ether; chloroform;

DOI:10.1016/S0040-4020(01)80960-1

upstream raw materials:

2,4-dibenzoyloxyacetophenone

2-hydroxyethanethiol

2',4'-dihydroxy-4-acetophenone

benzoyl chloride

Downstream raw materials:

2',4'-ditetrahydropyranyloxychalcone

2',4'-ditetrahydropyranyloxychalcone epoxide

2',4'-ditetrahydropyranyloxyacetophenone ethylene hemithioketal

2',4'-bis(tetrahydropyran-2-yloxy)acetophenone