66832-97-1Relevant articles and documents
One-pot synthesis of 3-fluoroflavones: Via 1-(2-hydroxyphenyl)-3-phenylpropane-1,3-diones and selectfluor at room temperature
Wang, Rui,Han, Jie,Li, Chenchen,Zhang, Jie,Liang, Yong,Wang, Tao,Zhang, Zunting
supporting information, p. 2479 - 2488 (2018/04/12)
A concise and efficient one-pot strategy to synthesize 3-fluoroflavones was developed. 1-(2-Hydroxyphenyl)-3-phenylpropane-1,3-diones were fluorinated using selectfluor with a small amount of CH3CN at room temperature, followed by cyclization a
Five-membered heterocycle (or amide)-flavonoid compound-matrine ternary conjugate and application thereof
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Paragraph 0039; 0040, (2016/10/08)
The invention discloses a five-membered heterocycle (or amide)-flavonoid compound-matrine ternary conjugate and application thereof. The five-membered heterocycle (or amide)-flavonoid compound-matrine ternary conjugate has a structure as shown in the specification, has an effective antibacterial activity, and has a potential application value in the aspect of antibacterial drug development. The five-membered heterocycle (or amide)-flavonoid compound-matrine ternary conjugate has a remarkable effect on the antibacterial aspect, and can be applied to prevention and treatment of MRSA, P.aeru, E.coli, Ab and other clinical common pathogens.
Crystal structure and luminescence properties of 4-(4-benzoyloxy-2- hydroxyphenyl)-2,2-difluoro-6-phenyl-1,3,2-dioxaborine
Bukvetskii,Fedorenko,Mirochnik
, p. 1991 - 1998 (2014/07/07)
The crystal structure of 4-(4-benzoyloxy-2-hydroxyphenyl)-2,2- difluoro6phenyl-1,3,2-dioxaborine (1) was determined by X-ray diffraction analysis. π-π-Stacking interaction between the molecules results in joining the molecules into a threedimensional laye
Reinvestigation of the synthesis of isoliquiritigenin: Application of Horner-Wadsworth-Emmons reaction and Claisen-Schmidt condensation
Sano, Shigeki,Okubo, Yoshinori,Handa, Atsushi,Nakao, Michiyasu,Kitaike, Syuji,Nagao, Yoshimitsu,Kakegawa, Hisao
scheme or table, p. 885 - 888 (2011/08/06)
Isoliquiritigenin [ILG, (E)-1] was readily prepared via the Horner-Wadsworth-Emmons reactions using β -ketophosphonates 5a, b. An improved protocol for the synthesis of (E)-1 via the Claisen-Schmidt condensation was also presented.
Design, synthesis and biological evaluation of new arylpiperazine derivatives bearing a flavone moiety as α1-adrenoceptor antagonists
Jin, Jing,Wang, Xiao-Bing,Kong, Ling-Yi
scheme or table, p. 909 - 911 (2011/03/20)
Elaborate study on the three-dimensional model of α1- adrenoceptor (α1-AR) antagonists led to the development of a series of new arylpiperazine derivatives bearing a flavone nucleus as α1-AR antagonists. The in vitro activities were evaluated and compounds 1, 4, 10, 13 and 15 showed activities close to the reference compound (Prazosin).
Synthesis, biopharmaceutical characterization, antimicrobial and antioxidant activities of 1-(4′-O-β-d-glucopyranosyloxy-2′- hydroxyphenyl)-3-aryl-propane-1,3-diones
Sheikh, Javed,Parvez, Ali,Juneja, Harjeet,Ingle, Vishwas,Chohan, Zahid,Youssoufi, Moulay,Ben Hadda, Taibi
experimental part, p. 1390 - 1399 (2011/04/23)
This research communication is toward the investigation of the antibacterial, antifungal and antioxidant activities of the synthesized compounds 1-(4′-O-β-d-glucopyranosyloxy-2′-hydroxyphenyl)-3- aryl-propane-1,3-diones (5a)-(5h). These compounds have bee
Facile synthesis of 7-methoxy-2-aryl-3-phenyl/or-H-8-[2-(4,6-dimethyl-3,5- dicarbethoxy-pyridyl)]-4H-1-benzopyran-4-ones
Soni, Anil Kumar,Krupadanam, G. L. David,Srimannarayana
, p. 795 - 804 (2007/10/03)
Condensation of 8-formyl-7-methoxy-2-phenyl-4H-1-benzopyran-4-ones (5a-f) with ethyl-3-aminocrotonate (6) in glacial acetic acid under Hantzsch conditions afforded 7-methoxy-2-aryl-3-phenyl/or-H-8-[2-(4,6-dimethyl-3,5-dicarbethoxy- pyridyl)]-4H-1-benzopyran-4-ones (7a-f) in good yields. Copyright Taylor & Francis Group, LLC.
PhCOCI-Py/basic alumina as a versatile reagent for benzoylation in solvent-free conditions
Paul, Satya,Nanda, Puja,Gupta, Rajive
, p. 374 - 380 (2007/10/03)
A solvent-free procedure using PhCOCl-Py/basic alumina under microwave irradiation has been developed for N-, O- and S-benzoylation.
Synthesis of 2'-hydroxychalcone epoxides
Adams,Main
, p. 4959 - 4978 (2007/10/05)
Various preparations of some 2'-tetrahydropyran-2-yloxychalcone epoxides and removal of their tetrahydropyranyl (THP) protective groups in slightly aqueous acidic dioxane are described. So synthesised were 2'-hydroxy-6'-isopropoxy- and 2'-hydroxy-6'-methoxychalcone epoxide, as well as the 2-CF3, 4-Cl and 4-NO2 analogues of the latter. 2',4'-dihydroxy-6'-methoxychalcone epoxide was similarly prepared. In some other 6'-methoxy cases protective group removal was accompanied by epoxide solvolysis and the corresponding α,β-dihydroxydihydrochalcone was the only isolable product [2-OMe, 4-OMe, 3,4,5-(OMe)3 cases] or a byproduct [4-Me case]. Similarly prepared by THP removal were 2'-hydroxy-4'-methoxychalcone epoxide and 2',4'-dihydroxychalcone epoxide, whereas an attempt to convert 2',6'-ditetrahydropyranyloxychalcone epoxide into 2',6'-dihydroxychalcone epoxide gave the product of cyclisation of the latter, 3,5-dihydroxyflavanone.