B-Phenyl-2-dboronic acid

Base Information

Chemical Name:B-Phenyl-2-dboronic acid
CAS No.:502925-48-6
Molecular Formula:C₆H₇BO₂
Molecular Weight:122.923
Hs Code.:
DSSTox Substance ID:DTXSID301313065

Synonyms:B-Phenyl-2-dboronic acid;DTXSID301313065;502925-48-6

Suppliers and Price of B-Phenyl-2-dboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of B-Phenyl-2-dboronic acid

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:123.0601864
Heavy Atom Count:9
Complexity:79.1

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:B(C1=CC=CC=C1)(O)O
Isomeric SMILES:[2H]C1=C(C=CC=C1)B(O)O

Technology Process of B-Phenyl-2-dboronic acid

There total 7 articles about B-Phenyl-2-dboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 5419-55-6
Triisopropyl borate

: 22069-99-4
1-bromo-2-deuterobenzene

: 502925-48-6
(2-deuteriophenyl)boronic acid

Guidance literature:: 1-bromo-2-deuterobenzene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 2.16667h; Inert atmosphere;

Triisopropyl borate; In tetrahydrofuran; at -78 - 20 ℃;

With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃; for 3h;
DOI:10.1021/acs.orglett.5b00392

Reference yield: 61.0%

: 121-43-7,63156-11-6
Trimethyl borate

: 22069-99-4
1-bromo-2-deuterobenzene

: 502925-48-6
(2-deuteriophenyl)boronic acid

Guidance literature:: 1-bromo-2-deuterobenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 2h; Inert atmosphere;

Trimethyl borate; In tetrahydrofuran; hexane; at -78 - 20 ℃;
DOI:10.1002/anie.202108814

Reference yield:

: 583-55-1
1-Bromo-2-iodobenzene

: 502925-48-6
(2-deuteriophenyl)boronic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: isopropylmagnesium chloride / tetrahydrofuran; diethyl ether / 2 h / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran / 2.5 h / -78 °C / Inert atmosphere

2.2: -78 - 20 °C / Inert atmosphere

With n-butyllithium; isopropylmagnesium chloride; In tetrahydrofuran; diethyl ether;
DOI:10.1021/ja300168m