Technology Process of 1-bromo-2-deuterobenzene
There total 10 articles about 1-bromo-2-deuterobenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2,3-dibromobenzene;
With
tert.-butyl lithium;
In
tetrahydrofuran; diethyl ether; pentane;
at -120 ℃;
for 0.5h;
With
diclazuril;
In
tetrahydrofuran; diethyl ether; pentane;
at -120 - -110 ℃;
for 0.5h;
Further stages.;
DOI:10.1021/jo7013033
- Guidance literature:
-
1-Bromo-2-iodobenzene;
With
isopropylmagnesium chloride;
In
tetrahydrofuran; water;
at -78 ℃;
for 2.25h;
Inert atmosphere;
With
d(4)-methanol;
In
tetrahydrofuran; water;
at -78 - 20 ℃;
DOI:10.1002/anie.202108814
- Guidance literature:
-
o-deuteriochlorobenzene;
With
magnesium; ethylene dibromide;
In
tetrahydrofuran;
at 20 - 80 ℃;
for 6h;
Inert atmosphere;
With
1,2-dibromo-1,1,2,2-tetrafluoroethane;
In
diethyl ether;
at 0 - 20 ℃;
for 0.416667h;
Inert atmosphere;
DOI:10.1021/ja302278s
