N-Anilino-3,4-dihydro-isochinoliniumbromid

Base Information

• Chemical Name: N-Anilino-3,4-dihydro-isochinoliniumbromid
• CAS No.: 21188-84-1
• Molecular Formula: Br*C₁₅H₁₅N₂
• Molecular Weight: 303.201
• Mol file: 21188-84-1.mol

Synonyms:N-Anilino-3,4-dihydro-isochinoliniumbromid

Chemical Property of N-Anilino-3,4-dihydro-isochinoliniumbromid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Anilino-3,4-dihydro-isochinoliniumbromid

There total 1 articles about N-Anilino-3,4-dihydro-isochinoliniumbromid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2-bromoethyl)benzaldehyde (22901-09-3) + phenylhydrazine (100-63-0) → N-Anilino-3,4-dihydro-isochinoliniumbromid (21188-84-1)

Guidance literature:

DOI:10.1002/(SICI)1099-0690(199802)1998:2<379::AID-EJOC379>3.0.CO;2-F

Reference yield: 80.0%

N-Anilino-3,4-dihydro-isochinoliniumbromid (21188-84-1) → N-anilinoisoquinolinium bromide

Guidance literature:

With Nitrosobenzene; In N,N-dimethyl-formamide; 20 deg C to 40 deg C, 20 min, 40 deg C, 3 h;

DOI:10.1002/(SICI)1099-0690(199802)1998:2<379::AID-EJOC379>3.0.CO;2-F

Reference yield: 41.0%

C6H5Cl2BNH2C6H2(CH3)3 + N-Anilino-3,4-dihydro-isochinoliniumbromid (21188-84-1) → C6H4(CH2)2NN(C6H5)B(C6H5)N(C6H2-2,4-6-(CH3)3)CH

Guidance literature:

With triethylamine; In chlorobenzene; byproducts: triethyl amine HCl; reacting N-anilino-3,4-dihydro-isochinolinium bromide with triethyl amine at 90-100°C, then adding aminoborane at room temp.; filtering the triethyl amine salt; distg. at 1E-3 Torr three times;

upstream raw materials:

2-(2-bromoethyl)benzaldehyde

phenylhydrazine

Downstream raw materials:

1-butyl-2-methyl-3-phenyl-1,2,3,5,6,10b-hexahydro-[1,2,4,3]triazaborolo[5,1-a]isoquinoline

1-(2,6-dimethyl-phenyl)-2-methyl-3-phenyl-1,2,3,5,6,10b-hexahydro-[1,2,4,3]triazaborolo[5,1-a]isoquinoline

1,3-diphenyl-1,10b-dihydro-[1,2,4]triazolo[5,1-a]isoquinolin-2-one

1,3-diphenyl-1,10b-dihydro-[1,2,4]triazolo[5,1-a]isoquinoline-2-thione

Refernces