N-<2-(dimethylamino)ethyl>4-(2-nitrobenzamido)2-nitrobenzamide

Base Information

• Chemical Name: N-<2-(dimethylamino)ethyl>4-(2-nitrobenzamido)2-nitrobenzamide
• CAS No.: 171116-84-0
• Molecular Formula: C₁₈H₁₉N₅O₆
• Molecular Weight: 401.379
• Mol file: 171116-84-0.mol

Synonyms:N-<2-(dimethylamino)ethyl>4-(2-nitrobenzamido)2-nitrobenzamide

Chemical Property of N-<2-(dimethylamino)ethyl>4-(2-nitrobenzamido)2-nitrobenzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-<2-(dimethylamino)ethyl>4-(2-nitrobenzamido)2-nitrobenzamide

There total 4 articles about N-<2-(dimethylamino)ethyl>4-(2-nitrobenzamido)2-nitrobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

N,N-dimethylethylenediamine (108-00-9) + 4-(2-nitrobenzamido)2-nitrobenzoic acid (171116-88-4) → N-<2-(dimethylamino)ethyl>4-(2-nitrobenzamido)2-nitrobenzamide (171116-84-0)

Guidance literature:

With 1,1'-carbonyldiimidazole; In N,N-dimethyl-formamide; at 0 ℃;

DOI:10.1002/poc.610080905

Reference yield:

4-amino-2-nitrobenzoic acid (610-36-6) → N-<2-(dimethylamino)ethyl>4-(2-nitrobenzamido)2-nitrobenzamide (171116-84-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 68 percent / Na₂CO₃ / H₂O / 0.5 h / 20 °C

2: 71 percent / 1,1-carbonyldiimidazole / dimethylformamide / 0 °C

With sodium carbonate; 1,1'-carbonyldiimidazole; In water; N,N-dimethyl-formamide;

DOI:10.1002/poc.610080905

Reference yield:

2-nitrobenzyl chloride (610-14-0) → N-<2-(dimethylamino)ethyl>4-(2-nitrobenzamido)2-nitrobenzamide (171116-84-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 68 percent / Na₂CO₃ / H₂O / 0.5 h / 20 °C

2: 71 percent / 1,1-carbonyldiimidazole / dimethylformamide / 0 °C

With sodium carbonate; 1,1'-carbonyldiimidazole; In water; N,N-dimethyl-formamide;

DOI:10.1002/poc.610080905

upstream raw materials:

4-amino-2-nitrobenzoic acid

N,N-dimethylethylenediamine

2-nitrobenzyl chloride

4-(2-nitrobenzamido)2-nitrobenzoic acid

Downstream raw materials:

2-(Acridin-9-ylamino)-4-benzoylamino-N-(2-dimethylamino-ethyl)-benzamide

C₃₁H₂₉N₅O₂