(E)-tert-butyl 1-benzyl-2-(3,5-dimethoxybenzylidene)hydrazinecarboxylate

Base Information

• Chemical Name: (E)-tert-butyl 1-benzyl-2-(3,5-dimethoxybenzylidene)hydrazinecarboxylate
• CAS No.: 1338091-85-2
• Molecular Formula: C₂₁H₂₆N₂O₄
• Molecular Weight: 370.448
• Mol file: 1338091-85-2.mol

Synonyms:(E)-tert-butyl 1-benzyl-2-(3,5-dimethoxybenzylidene)hydrazinecarboxylate

Chemical Property of (E)-tert-butyl 1-benzyl-2-(3,5-dimethoxybenzylidene)hydrazinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-tert-butyl 1-benzyl-2-(3,5-dimethoxybenzylidene)hydrazinecarboxylate

There total 3 articles about (E)-tert-butyl 1-benzyl-2-(3,5-dimethoxybenzylidene)hydrazinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(E)-tert-butyl 2-(3,5-dimethoxybenzylidene)hydrazinecarboxylate (106728-65-8) + benzyl bromide (100-39-0) → (E)-tert-butyl 1-benzyl-2-(3,5-dimethoxybenzylidene)hydrazinecarboxylate (1338091-85-2)

Guidance literature:

With caesium carbonate; at 20 ℃; for 1h; Neat (no solvent); Ball-milling;

DOI:10.1016/j.tet.2011.07.056

Reference yield:

t-butoxycarbonylhydrazine (870-46-2) → (E)-tert-butyl 1-benzyl-2-(3,5-dimethoxybenzylidene)hydrazinecarboxylate (1338091-85-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1 h / 20 °C / Neat (no solvent); Ball-milling

2: caesium carbonate / 1 h / 20 °C / Neat (no solvent); Ball-milling

With caesium carbonate;

DOI:10.1016/j.tet.2011.07.056

Reference yield:

3,5-dimethoxybenzaldehdye (7311-34-4) → (E)-tert-butyl 1-benzyl-2-(3,5-dimethoxybenzylidene)hydrazinecarboxylate (1338091-85-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1 h / 20 °C / Neat (no solvent); Ball-milling

2: caesium carbonate / 1 h / 20 °C / Neat (no solvent); Ball-milling

With caesium carbonate;

DOI:10.1016/j.tet.2011.07.056

upstream raw materials:

(E)-tert-butyl 2-(3,5-dimethoxybenzylidene)hydrazinecarboxylate

benzyl bromide

t-butoxycarbonylhydrazine

3,5-dimethoxybenzaldehdye