Technology Process of 2,2,2-Trichloroethyl 2,6-Dimethoxy-3-pivaloylbenzoate
There total 5 articles about 2,2,2-Trichloroethyl 2,6-Dimethoxy-3-pivaloylbenzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
In
chloroform; trifluoroacetic acid;
at 60 ℃;
for 16h;
DOI:10.1021/jo00065a015
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1) SOCl2, DMF / 1) toluene, 2) CH2Cl2, overnight
2: trifluoroacetic anhydride / 1) 40 deg C, 8 h, 2) rt, 16 h
3: m-chloroperbenzoic acid, p-TsOH / CHCl3 / 24 h / Ambient temperature
4: aq. HCl / acetone / 6 h / 60 °C
5: 89 percent / CHCl3; trifluoroacetic acid / 16 h / 60 °C
With
hydrogenchloride; thionyl chloride; toluene-4-sulfonic acid; N,N-dimethyl-formamide; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic anhydride;
In
chloroform; acetone; trifluoroacetic acid;
DOI:10.1021/jo00065a015
- Guidance literature:
-
Multi-step reaction with 4 steps
1: trifluoroacetic anhydride / 1) 40 deg C, 8 h, 2) rt, 16 h
2: m-chloroperbenzoic acid, p-TsOH / CHCl3 / 24 h / Ambient temperature
3: aq. HCl / acetone / 6 h / 60 °C
4: 89 percent / CHCl3; trifluoroacetic acid / 16 h / 60 °C
With
hydrogenchloride; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic anhydride;
In
chloroform; acetone; trifluoroacetic acid;
DOI:10.1021/jo00065a015
