2-Iodo-4,6-dimethoxybenzaldehyde

Base Information

Chemical Name:2-Iodo-4,6-dimethoxybenzaldehyde
CAS No.:16147-09-4
Molecular Formula:C₉H₉IO₃
Molecular Weight:292.073
Hs Code.:
DSSTox Substance ID:DTXSID501301983
Nikkaji Number:J2.161.870E

Synonyms:2-Iodo-4,6-dimethoxybenzaldehyde;16147-09-4;SCHEMBL5943337;2-Jod-4,6-dimethoxybenzaldehyd;DTXSID501301983;CS-0498364

Suppliers and Price of 2-Iodo-4,6-dimethoxybenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Iodo-4,6-dimethoxybenzaldehyde

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:291.95964
Heavy Atom Count:13
Complexity:174

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=C(C(=C1)I)C=O)OC

Technology Process of 2-Iodo-4,6-dimethoxybenzaldehyde

There total 4 articles about 2-Iodo-4,6-dimethoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 25245-27-6
1-iodo-3,5-dimethoxybenzene

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 16147-09-4
2-iodo-4,6-dimethoxybenzaldehyde

Guidance literature:: With trichlorophosphate; at 0 - 100 ℃; for 16h;
DOI:10.1039/d1cc02257a

Reference yield:

: 10272-07-8
3.5-dimethoxyaniline

: 16147-09-4
2-iodo-4,6-dimethoxybenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaNO₂; HCl / H₂O

1.2: 55 percent / KI / H₂O / Sandmeyer substitution reaction

2.1: 64 percent / POCl₃

With hydrogenchloride; sodium nitrite; trichlorophosphate; In water; 2.1: Vilsmeier reaction;
DOI:10.1016/j.tetlet.2005.03.046