1,1-dimethylethyl 4-[(6-[4-fluoro-3-(trifluoromethyl)phenyl]-5-{2-[(1-methylethyl)amino]-2-oxoethyl}-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazin-2-yl)oxy]-1-piperidinecarboxylate

Base Information

Chemical Name:1,1-dimethylethyl 4-[(6-[4-fluoro-3-(trifluoromethyl)phenyl]-5-{2-[(1-methylethyl)amino]-2-oxoethyl}-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazin-2-yl)oxy]-1-piperidinecarboxylate
CAS No.:1192313-88-4
Molecular Formula:C₂₈H₃₃F₄N₅O₅
Molecular Weight:595.594
Hs Code.:

1,1-dimethylethyl 4-[(6-[4-fluoro-3-(trifluoromethyl)phenyl]-5-{2-[(1-methylethyl)amino]-2-oxoethyl}-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazin-2-yl)oxy]-1-piperidinecarboxylate

Synonyms:1,1-dimethylethyl 4-[(6-[4-fluoro-3-(trifluoromethyl)phenyl]-5-{2-[(1-methylethyl)amino]-2-oxoethyl}-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazin-2-yl)oxy]-1-piperidinecarboxylate

Suppliers and Price of 1,1-dimethylethyl 4-[(6-[4-fluoro-3-(trifluoromethyl)phenyl]-5-{2-[(1-methylethyl)amino]-2-oxoethyl}-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazin-2-yl)oxy]-1-piperidinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,1-dimethylethyl 4-[(6-[4-fluoro-3-(trifluoromethyl)phenyl]-5-{2-[(1-methylethyl)amino]-2-oxoethyl}-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazin-2-yl)oxy]-1-piperidinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,1-dimethylethyl 4-[(6-[4-fluoro-3-(trifluoromethyl)phenyl]-5-{2-[(1-methylethyl)amino]-2-oxoethyl}-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazin-2-yl)oxy]-1-piperidinecarboxylate

There total 5 articles about 1,1-dimethylethyl 4-[(6-[4-fluoro-3-(trifluoromethyl)phenyl]-5-{2-[(1-methylethyl)amino]-2-oxoethyl}-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazin-2-yl)oxy]-1-piperidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2895-21-8
2-chloro-N-isopropylacetamide

: 1192313-87-3
1,1-dimethylethyl 4-({6-[4-fluoro-3-(trifluoromethyl)phenyl]-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazin-2-yl}oxy)-1-piperidinecarboxylate

: 1192313-88-4
1,1-dimethylethyl 4-[(6-[4-fluoro-3-(trifluoromethyl)phenyl]-5-{2-[(1-methylethyl)amino]-2-oxoethyl}-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazin-2-yl)oxy]-1-piperidinecarboxylate

Guidance literature:: 1,1-dimethylethyl 4-({6-[4-fluoro-3-(trifluoromethyl)phenyl]-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazin-2-yl}oxy)-1-piperidinecarboxylate; With sodium hydride; In 1,2-dimethoxyethane; N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere of nitrogen;

2-chloro-N-isopropylacetamide; With sodium iodide; lithium bromide; In 1,2-dimethoxyethane; N,N-dimethyl-formamide; at 0 - 70 ℃; for 0.0833333h;

2-chloro-N-isopropylacetamide;

Reference yield:

: 537050-14-9
2-bromo-1-(4-fluoro-3-(trifluoromethyl)phenyl)ethan-1-one

: 1192313-88-4
1,1-dimethylethyl 4-[(6-[4-fluoro-3-(trifluoromethyl)phenyl]-5-{2-[(1-methylethyl)amino]-2-oxoethyl}-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazin-2-yl)oxy]-1-piperidinecarboxylate

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium carbonate / N,N-dimethyl-formamide / 20 °C

2.1: ammonium acetate; acetic acid / 24 h / 130 °C

3.1: dichloromethane / 2 h

4.1: sodium hydride / 1,2-dimethoxyethane; N,N-dimethyl-formamide / 20 °C / Inert atmosphere of nitrogen

4.2: 0.08 h / 0 - 70 °C

With ammonium acetate; sodium hydride; sodium carbonate; acetic acid; In 1,2-dimethoxyethane; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: C₁₈H₁₆F₄N₄O₂

: 1192313-88-4
1,1-dimethylethyl 4-[(6-[4-fluoro-3-(trifluoromethyl)phenyl]-5-{2-[(1-methylethyl)amino]-2-oxoethyl}-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazin-2-yl)oxy]-1-piperidinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: dichloromethane / 2 h

2.1: sodium hydride / 1,2-dimethoxyethane; N,N-dimethyl-formamide / 20 °C / Inert atmosphere of nitrogen

2.2: 0.08 h / 0 - 70 °C

With sodium hydride; In 1,2-dimethoxyethane; dichloromethane; N,N-dimethyl-formamide;