2-(Bromodifluoromethyl)-1,3-benzoxazole

Base Information

Chemical Name:2-(Bromodifluoromethyl)-1,3-benzoxazole
CAS No.:186828-50-2
Molecular Formula:
Molecular Weight:248.027
Hs Code.:2934999090
DSSTox Substance ID:DTXSID90443467
Nikkaji Number:J999.659A
Wikidata:Q82261311
Mol file:186828-50-2.mol

Synonyms:2-(Bromodifluoromethyl)-1,3-benzoxazole;186828-50-2;2-[bromo(difluoro)methyl]-1,3-benzoxazole;2-(Bromodifluoromethyl)benzo[d]oxazole;2-(bromodifluoromethyl)benzoxazole;bromodifluoromethyl benzoxazole;SCHEMBL21488100;DTXSID90443467;QJYISAVBXVIYNO-UHFFFAOYSA-N;MFCD11035866;AKOS025310292;PS-6530;E89163;A813088;2-[bromanyl-bis(fluoranyl)methyl]-1,3-benzoxazole

Suppliers and Price of 2-(Bromodifluoromethyl)-1,3-benzoxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-(Bromodifluoromethyl)-1,3-benzoxazole
1 g
$ 125.00

SynQuest Laboratories
2-(Bromodifluoromethyl)-1,3-benzoxazole
5 g
$ 295.00

Crysdot
2-(Bromodifluoromethyl)benzo[d]oxazole 97%
5g
$ 499.00

Apolloscientific
2-(Bromodifluoromethyl)-1,3-benzoxazole
5g
$ 205.00

Apolloscientific
2-(Bromodifluoromethyl)-1,3-benzoxazole
1g
$ 55.00

American Custom Chemicals Corporation
2-(BROMODIFLUOROMETHYL)-1,3-BENZOXAZOLE 95.00%
5G
$ 1049.09

American Custom Chemicals Corporation
2-(BROMODIFLUOROMETHYL)-1,3-BENZOXAZOLE 95.00%
1G
$ 657.54

Total 12 raw suppliers

Chemical Property of 2-(Bromodifluoromethyl)-1,3-benzoxazole

Chemical Property:

Vapor Pressure:0.467mmHg at 25°C
Refractive Index:1.583
Boiling Point:200.1°Cat760mmHg
Flash Point:74.8°C
PSA：26.03000
Density:1.761g/cm³
LogP:3.27200
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:246.94443
Heavy Atom Count:13
Complexity:203

Purity/Quality:

97% ^*data from raw suppliers

2-(Bromodifluoromethyl)-1,3-benzoxazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)N=C(O2)C(F)(F)Br

Technology Process of 2-(Bromodifluoromethyl)-1,3-benzoxazole

There total 1 articles about 2-(Bromodifluoromethyl)-1,3-benzoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 354-08-5
bromodifluoroacetic acid

: 95-55-6
2-amino-phenol

: 186828-50-2
2-(1-bromodifluoromethyl)benzo-1,3-oxazole

Guidance literature:: bromodifluoroacetic acid; With carbon tetrabromide; triethylamine; triphenylphosphine; In toluene; at 0 ℃; for 0.166667h; Inert atmosphere;

2-amino-phenol; In toluene; for 8h; Inert atmosphere; Reflux;
DOI:10.1016/j.jfluchem.2011.08.008

Reference yield: 96.0%

: 1426399-44-1
p-iodobenzoic acid pent-1-ene ester

: 186828-50-2
2-(1-bromodifluoromethyl)benzo-1,3-oxazole

: (E)-6-(benzo[d]oxazol-2-yl)-6,6-difluorohex-4-en-1-yl 4-iodobenzoate

Guidance literature:: With 1,10-Phenanthroline; tetrakis(acetonitrile)copper(I)tetrafluoroborate; caesium carbonate; In 1,2-dichloro-ethane; at 80 ℃; for 7h;

Reference yield: 95.0%

: 186828-50-2
2-(1-bromodifluoromethyl)benzo-1,3-oxazole

: 98-80-6
phenylboronic acid

: 1351669-69-6
2-(difluoro(phenyl)methyl)benzo[d]oxazole

Guidance literature:: With palladium diacetate; potassium carbonate; di(1-adamantyl)-N-butylphosphine hydroiodide; In 1,4-dioxane; at 70 ℃; for 7h; Reagent/catalyst; Temperature; Concentration; Solvent; Schlenk technique;
DOI:10.1021/ol502121m