(3S,4S)-1-benzyl-4-(tert-butoxycarbonyl)amino-4-methoxycarbonyl-3-methyl-2-oxoazepane

Base Information

Chemical Name:(3S,4S)-1-benzyl-4-(tert-butoxycarbonyl)amino-4-methoxycarbonyl-3-methyl-2-oxoazepane
CAS No.:1252809-39-4
Molecular Formula:C₂₁H₃₀N₂O₅
Molecular Weight:390.48
Hs Code.:

Synonyms:(3S,4S)-1-benzyl-4-(tert-butoxycarbonyl)amino-4-methoxycarbonyl-3-methyl-2-oxoazepane

Suppliers and Price of (3S,4S)-1-benzyl-4-(tert-butoxycarbonyl)amino-4-methoxycarbonyl-3-methyl-2-oxoazepane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S,4S)-1-benzyl-4-(tert-butoxycarbonyl)amino-4-methoxycarbonyl-3-methyl-2-oxoazepane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,4S)-1-benzyl-4-(tert-butoxycarbonyl)amino-4-methoxycarbonyl-3-methyl-2-oxoazepane

There total 10 articles about (3S,4S)-1-benzyl-4-(tert-butoxycarbonyl)amino-4-methoxycarbonyl-3-methyl-2-oxoazepane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1252809-37-2
(3S,4S)-4-tert-butoxycarbonyl-4-(tert-butoxycarbonyl)amino-3-methyl-2-oxoazepane

: 100-39-0
benzyl bromide

: 1252809-39-4
(3S,4S)-1-benzyl-4-(tert-butoxycarbonyl)amino-4-methoxycarbonyl-3-methyl-2-oxoazepane

Guidance literature:: With tert-butylimino-tri(pyrrolidino)phosphorane; In acetonitrile; at 120 ℃; for 0.75h; Microwave irradiation;
DOI:10.1021/jo200894d

Reference yield: 91.0%

: 1252809-31-6
(3S,4S)-4-(tert-butoxycarbonyl)amino-4-methoxycarbonyl-3-methyl-2-oxoazepane

: 100-39-0
benzyl bromide

: 1252809-39-4
(3S,4S)-1-benzyl-4-(tert-butoxycarbonyl)amino-4-methoxycarbonyl-3-methyl-2-oxoazepane

Guidance literature:: With tert-butylimino-tri(pyrrolidino)phosphorane; In acetonitrile; Microwave irradiation;
DOI:10.1039/c5ob00429b

Reference yield:

: 1252809-29-2
(3S,4S)-4-[3'-(benzyloxycarbonyl)amino]propyl-4-methoxycarbonyl-3-methyl-2-oxoazetidine

: 1252809-39-4
(3S,4S)-1-benzyl-4-(tert-butoxycarbonyl)amino-4-methoxycarbonyl-3-methyl-2-oxoazepane

Guidance literature:: Multi-step reaction with 3 steps

1: dmap; triethylamine / dichloromethane / 3 h

2: palladium 10% on activated carbon; hydrogen / methanol / 2 h / 20 °C / 760.05 Torr

3: tert-butylimino-tri(pyrrolidino)phosphorane / acetonitrile / Microwave irradiation

With dmap; palladium 10% on activated carbon; hydrogen; triethylamine; tert-butylimino-tri(pyrrolidino)phosphorane; In methanol; dichloromethane; acetonitrile;
DOI:10.1039/c5ob00429b