2-<(5-amino-6,7-dihydro-7-oxo-3H-1,2,3-triazolo<4,5-d>pyrimidin-3-yl)methoxy>ethyl benzoate

Base Information

• Chemical Name: 2-<(5-amino-6,7-dihydro-7-oxo-3H-1,2,3-triazolo<4,5-d>pyrimidin-3-yl)methoxy>ethyl benzoate
• CAS No.: 96445-98-6
• Molecular Formula: C₁₄H₁₄N₆O₄
• Molecular Weight: 330.303
• Mol file: 96445-98-6.mol

Synonyms:2-<(5-amino-6,7-dihydro-7-oxo-3H-1,2,3-triazolo<4,5-d>pyrimidin-3-yl)methoxy>ethyl benzoate

Chemical Property of 2-<(5-amino-6,7-dihydro-7-oxo-3H-1,2,3-triazolo<4,5-d>pyrimidin-3-yl)methoxy>ethyl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-<(5-amino-6,7-dihydro-7-oxo-3H-1,2,3-triazolo<4,5-d>pyrimidin-3-yl)methoxy>ethyl benzoate

There total 5 articles about 2-<(5-amino-6,7-dihydro-7-oxo-3H-1,2,3-triazolo<4,5-d>pyrimidin-3-yl)methoxy>ethyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-benzoyloxyethoxymethyl acetate (63590-60-3) + 8-azaguanine (134-58-7) → 2-<(5-amino-6,7-dihydro-7-oxo-3H-1,2,3-triazolo<4,5-d>pyrimidin-3-yl)methoxy>ethyl benzoate (96445-98-6)

Guidance literature:

With ammonium sulfate; toluene-4-sulfonic acid; 1,1,1,3,3,3-hexamethyl-disilazane; In methanol; chloroform; mineral oil;

Reference yield:

ammonium sulfate + (2-benzoyloxyethyl)oxymethyl chloride (58305-05-8) + 8-azaguanine (134-58-7) → 2-<(5-amino-6,7-dihydro-7-oxo-3H-1,2,3-triazolo<4,5-d>pyrimidin-3-yl)methoxy>ethyl benzoate (96445-98-6)

Guidance literature:

In ethanol; 1,1,1,3,3,3-hexamethyl-disilazane; acetonitrile;

Reference yield:

C9H10O3 (94-33-7) → 2-<(5-amino-6,7-dihydro-7-oxo-3H-1,2,3-triazolo<4,5-d>pyrimidin-3-yl)methoxy>ethyl benzoate (96445-98-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / HCl gas / 1,2-dichloro-ethane / 3 h / 0 °C

2: 0.32 g / acetonitrile / 144 h / Ambient temperature

With hydrogenchloride; In 1,2-dichloro-ethane; acetonitrile;

DOI:10.1021/jm00146a002

upstream raw materials:

(2-benzoyloxyethyl)oxymethyl chloride

C₉H₁₀O₃

8-azaguanine

2-benzoyloxyethoxymethyl acetate