Technology Process of 3-chloro-2-ethylphenyl diethylcarbamate
There total 2 articles about 3-chloro-2-ethylphenyl diethylcarbamate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 2 h / 20 °C
1.2: 3 h
2.1: N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium / tetrahydrofuran / 2 h / -70 °C
2.2: -70 - 20 °C
With
N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; sodium hydride;
In
tetrahydrofuran;
- Guidance literature:
-
3-chlorophenyl N,N-diethylcarbamate;
With
N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium;
In
tetrahydrofuran;
at -70 ℃;
for 2h;
ethyl iodide;
In
tetrahydrofuran;
at -70 - 20 ℃;
for 1h;
- Guidance literature:
-
3-chloro-2-ethylphenyl diethylcarbamate;
With
sodium hydroxide;
In
ethanol;
at 20 - 120 ℃;
for 1.5h;
Microwave irradiation;
Sealed;
With
hydrogenchloride;
In
water;
pH=6;
Cooling with ice;
