(2-{2-[2-(2-ethoxycarbonylmethoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-acetic acid benzyl ester

Base Information

• Chemical Name: (2-{2-[2-(2-ethoxycarbonylmethoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-acetic acid benzyl ester
• CAS No.: 339547-43-2
• Molecular Formula: C₂₁H₃₂O₉
• Molecular Weight: 428.48
• Mol file: 339547-43-2.mol

Synonyms:(2-{2-[2-(2-ethoxycarbonylmethoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-acetic acid benzyl ester

Chemical Property of (2-{2-[2-(2-ethoxycarbonylmethoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-acetic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-{2-[2-(2-ethoxycarbonylmethoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-acetic acid benzyl ester

There total 3 articles about (2-{2-[2-(2-ethoxycarbonylmethoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-acetic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

diazoacetic acid ethyl ester (623-73-4) + 14-hydroxy-3,6,9,12-tetraoxatetradecanoic acid phenylmethyl ester (195071-47-7) → (2-{2-[2-(2-ethoxycarbonylmethoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-acetic acid benzyl ester (339547-43-2)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; for 12h;

DOI:10.1002/1521-3765(20010302)7:5<1095::AID-CHEM1095>3.0.CO;2-B

Reference yield:

Tetraethylene glycol (112-60-7) → (2-{2-[2-(2-ethoxycarbonylmethoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-acetic acid benzyl ester (339547-43-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 53 percent / BF₃*OEt₂ / CH₂Cl₂ / 6 h

2: 53 percent / BF₃*OEt₂ / CH₂Cl₂ / 12 h

With boron trifluoride diethyl etherate; In dichloromethane;

DOI:10.1002/1521-3765(20010302)7:5<1095::AID-CHEM1095>3.0.CO;2-B

Reference yield:

benzyl diazoacetate (52267-51-3) → (2-{2-[2-(2-ethoxycarbonylmethoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-acetic acid benzyl ester (339547-43-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 53 percent / BF₃*OEt₂ / CH₂Cl₂ / 6 h

2: 53 percent / BF₃*OEt₂ / CH₂Cl₂ / 12 h

With boron trifluoride diethyl etherate; In dichloromethane;

DOI:10.1002/1521-3765(20010302)7:5<1095::AID-CHEM1095>3.0.CO;2-B

upstream raw materials:

diazoacetic acid ethyl ester

14-hydroxy-3,6,9,12-tetraoxatetradecanoic acid phenylmethyl ester

Tetraethylene glycol

benzyl diazoacetate