Biotin-PEG7-Azide

Base Information

• Chemical Name: Biotin-PEG7-Azide
• CAS No.: 1334172-75-6
• Molecular Formula: C₂₆H₄₈N₆O₉S
• Molecular Weight: 620.768
• Hs Code.: 2942000090
• Mol file: 1334172-75-6.mol

Synonyms:α-(2-azidoethyl)-ω-(2-(5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido)ethoxy)hexa(oxyethylene)

Chemical Property of Biotin-PEG7-Azide

Chemical Property:

• Storage Temp.: -20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Biotin-PEG7-azide 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Biotin-PEG7-azide is PEG-containing click chemistry tool for biotinylation

Technology Process of Biotin-PEG7-Azide

There total 5 articles about Biotin-PEG7-Azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

α-amino,ω-azido,α,ω-dideoxy-octaethyleneglycol (1333154-77-0) + biotin (58-85-5,22879-79-4) → α-(2-azidoethyl)-ω-(2-(5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido)ethoxy)hexa(oxyethylene) (1334172-75-6)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 0 - 20 ℃;

DOI:10.1055/s-0032-1318433

Reference yield:

α-(2-azidoethyl)-ω-(formylmethoxy)hexa(oxyethylene) (1446411-31-9) → α-(2-azidoethyl)-ω-(2-(5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido)ethoxy)hexa(oxyethylene) (1334172-75-6)

Guidance literature:

Multi-step reaction with 2 steps

1: ammonium formate; acetic acid; sodium cyanoborohydride / water; methanol / 20 °C

2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 0 - 20 °C

With ammonium formate; sodium cyanoborohydride; benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In methanol; water; N,N-dimethyl-formamide;

DOI:10.1055/s-0032-1318433

Reference yield:

Tetraethylene glycol (112-60-7) → α-(2-azidoethyl)-ω-(2-(5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido)ethoxy)hexa(oxyethylene) (1334172-75-6)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.33 h

1.2: 20 °C

2.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.33 h

2.2: 20 °C

3.1: ozone / dichloromethane / 0.25 h / -78 °C

3.2: -78 - 20 °C / Inert atmosphere

4.1: ammonium formate; acetic acid; sodium cyanoborohydride / water; methanol / 20 °C

5.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 0 - 20 °C

With ammonium formate; sodium hydride; sodium cyanoborohydride; benzotriazol-1-ol; ozone; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In methanol; dichloromethane; water; N,N-dimethyl-formamide; mineral oil;

DOI:10.1055/s-0032-1318433

upstream raw materials:

α-(2-azidoethyl)-ω-(formylmethoxy)hexa(oxyethylene)

α-amino,ω-azido,α,ω-dideoxy-octaethyleneglycol

biotin

Tetraethylene glycol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1334172-75-6 Biotin-PEG7-Azide

Send

Send

Metric Ton KG G Pound L ML

Send

Send