tert-Butyl 2-hydroxy-2-methylpropylcarbamate

Base Information

Chemical Name:tert-Butyl 2-hydroxy-2-methylpropylcarbamate
CAS No.:183059-24-7
Molecular Formula:C9H19 N O3
Molecular Weight:189.255
Hs Code.:2924199090
DSSTox Substance ID:DTXSID60455375
Nikkaji Number:J776.767F
Wikidata:Q82277337
Mol file:183059-24-7.mol

Synonyms:183059-24-7;tert-Butyl 2-hydroxy-2-methylpropylcarbamate;tert-butyl N-(2-hydroxy-2-methylpropyl)carbamate;N-Boc-1-amino-2-methyl-2-propanol;1-Boc-amino-2-methyl-propan-2-ol;tert-butyl (2-hydroxy-2-methylpropyl)carbamate;MFCD09608009;Carbamic acid, (2-hydroxy-2-methylpropyl)-, 1,1-dimethylethyl ester;Carbamic acid, (2-hydroxy-2-methylpropyl)-, 1,1-dimethylethyl ester (9CI);SCHEMBL842921;DTXSID60455375;QBCNEFPGRLUXLR-UHFFFAOYSA-N;AKOS006331271;Carbamic acid, N-(2-hydroxy-2-methylpropyl)-, 1,1-dimethylethyl ester;CS-W019142;GS-3864;SY034546;tert-Butyl2-hydroxy-2-methylpropylcarbamate;FT-0756695;EN300-1880729;2-Methyl-3-(tert-butoxycarbonylamino)propan-2-ol;A880854;2-hydroxy-2-methylpropylcarbamic acid tert-butyl ester;2-Hydroxy-2-methylpropylcarbamic acid tert-butylester;2-hydroxy-2-methyl-propyl-carbamic acid tert-butyl ester;(2-hydroxy-2-methyl-propyl)-carbamic acid tert-butyl ester

Suppliers and Price of tert-Butyl 2-hydroxy-2-methylpropylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-Butyl2-Hydroxy-2-methylpropylcarbamate
50mg
$ 45.00

Matrix Scientific
tert-Butyl 2-hydroxy-2-methylpropylcarbamate 95+%
1g
$ 359.00

Matrix Scientific
tert-Butyl 2-hydroxy-2-methylpropylcarbamate 95+%
5g
$ 1079.00

Crysdot
tert-Butyl2-hydroxy-2-methylpropylcarbamate 98%
10g
$ 706.00

Crysdot
tert-Butyl2-hydroxy-2-methylpropylcarbamate 98%
5g
$ 424.00

Chemenu
N-Boc-1-amino-2-methyl-2-propanol 98%
5g
$ 400.00

Chemenu
N-Boc-1-amino-2-methyl-2-propanol 98%
10g
$ 667.00

Chemenu
N-Boc-1-amino-2-methyl-2-propanol 98%
1g
$ 146.00

Biosynth Carbosynth
tert-Butyl 2-hydroxy-2-methylpropylcarbamate
2 g
$ 325.00

Biosynth Carbosynth
tert-Butyl 2-hydroxy-2-methylpropylcarbamate
1 g
$ 187.00

Total 17 raw suppliers

Chemical Property of tert-Butyl 2-hydroxy-2-methylpropylcarbamate

Chemical Property:

PSA：62.05000
LogP:1.48640
Storage Temp.:2-8°C
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:189.13649347
Heavy Atom Count:13
Complexity:182

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl2-Hydroxy-2-methylpropylcarbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCC(C)(C)O

Technology Process of tert-Butyl 2-hydroxy-2-methylpropylcarbamate

There total 2 articles about tert-Butyl 2-hydroxy-2-methylpropylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 31954-27-5
N-(tert-butoxycarbonyl)glycine methyl ester

: 75-16-1
methylmagnesium bromide

: 183059-24-7
tert-butyl (2-hydroxy-2-methylpropyl)carbamate

Guidance literature:: In tetrahydrofuran;
DOI:10.1016/j.tetlet.2004.01.003

Reference yield:

: 31954-27-5
N-(tert-butoxycarbonyl)glycine methyl ester

: 74-88-4
methyl iodide

: 183059-24-7
tert-butyl (2-hydroxy-2-methylpropyl)carbamate

Guidance literature:: With magnesium; Yield given; Multistep reaction; 1.) Et₂O, reflux, 2.) Et₂O, r.t., 48 h;
DOI:10.1039/a809715a

Reference yield:

: (7S)-3-(3-amino-1-methyl-1H-indazol-6-yl)-7-methyl-5-(4-(trifluoromethyl)phenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one

: 530-62-1
1,1'-carbonyldiimidazole

: 183059-24-7
tert-butyl (2-hydroxy-2-methylpropyl)carbamate

: 1-((tert-butoxycarbonyl)amino)-2-methylpropan-2-yl (1-methyl-6-((7S)-7-methyl-4-oxo-5-(4-(trifluoromethyl)phenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-yl)-1H-indazol-3-yl)carbamate

Guidance literature:: (7S)-3-(3-amino-1-methyl-1H-indazol-6-yl)-7-methyl-5-(4-(trifluoromethyl)phenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one; 1,1'-carbonyldiimidazole; With N-ethyl-N,N-diisopropylamine; In chloroform; for 0.5h; Cooling with ice;

tert-butyl (2-hydroxy-2-methylpropyl)carbamate; In chloroform; at 70 ℃; for 2h;