Furo[2,3-b]pyridine 7-oxide

Base Information

• Chemical Name: Furo[2,3-b]pyridine 7-oxide
• CAS No.: 181526-16-9
• Molecular Formula: C₇H₅NO₂
• Molecular Weight: 135.122
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID40442324
• Nikkaji Number: J829.424K
• Wikidata: Q82259538
• Mol file: 181526-16-9.mol

Synonyms:Furo[2,3-b]pyridine 7-oxide;181526-16-9;7-oxidofuro[2,3-b]pyridin-7-ium;Furo[2,3-b]pyridine, 7-oxide (9CI);Furo(2,3-b)pyridine 7-oxide;Furo[2,3-b]pyridine7-oxide;SCHEMBL22554001;DTXSID40442324;AKOS016011630

Chemical Property of Furo[2,3-b]pyridine 7-oxide

Chemical Property:

• PSA: 38.60000
• LogP: 1.86130
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 135.032028402
• Heavy Atom Count: 10
• Complexity: 129

Purity/Quality:

98%min ^*data from raw suppliers

FURO[2,3-B]PYRIDINE 7-OXIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C([N+](=C1)[O-])OC=C2

Technology Process of Furo[2,3-b]pyridine 7-oxide

There total 1 articles about Furo[2,3-b]pyridine 7-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

furo<2,3-b>pyridine (272-01-5) → furo[2,3-b]pyridine 7-oxide (181526-16-9)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; for 22h; Ambient temperature;

DOI:10.1002/jhet.5570330321

Reference yield: 77.0%

trimethylsilyl cyanide (7677-24-9) + furo[2,3-b]pyridine 7-oxide (181526-16-9) → 6-cyanofuro<2,3-b>pyridine (190957-74-5)

Guidance literature:

With triethylamine; In acetonitrile; at 100 - 110 ℃; for 18h;

DOI:10.1002/jhet.5570340223

Reference yield: 69.0%

furo[2,3-b]pyridine 7-oxide (181526-16-9) → 6-chlorofuro[2,3-b]pyridine + 4-chlorofuro[2,3-b]pyridine (193624-86-1)

Guidance literature:

With trichlorophosphate; In chloroform; for 1.5h; Heating;

DOI:10.1002/jhet.5570340333

upstream raw materials:

furo<2,3-b>pyridine

Downstream raw materials:

6-cyanofuro<2,3-b>pyridine

6-phenylfuro<2,3-b>pyridine

4-chlorofuro[2,3-b]pyridine

4-methoxyfuro[2,3-b]pyridine

Refernces