N-(2-chloro-5-(6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide

Base Information

Chemical Name:N-(2-chloro-5-(6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide
CAS No.:1201842-65-0
Molecular Formula:C₂₁H₁₆ClN₃O₃S
Molecular Weight:425.895
Hs Code.:

Synonyms:N-(2-chloro-5-(6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide

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Chemical Property of N-(2-chloro-5-(6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide

Chemical Property:

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Technology Process of N-(2-chloro-5-(6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide

There total 3 articles about N-(2-chloro-5-(6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1112982-81-6
N-(5-bromo-2-chloropyridin-3-yl)-4-methoxybenzenesulfonamide

: 406463-06-7
6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)quinoline

: 1201842-65-0
N-(2-chloro-5-(6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; at 90 ℃; for 4h; Inert atmosphere;

Reference yield:

: 588729-99-1
3-amino-5-bromo-2-chloropyridine

: 1201842-65-0
N-(2-chloro-5-(6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium hexamethyldisilazane / tetrahydrofuran / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / ethanol / 4 h / 90 °C / Inert atmosphere

With sodium carbonate; lithium hexamethyldisilazane; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; ethanol;

Reference yield:

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 1201842-65-0
N-(2-chloro-5-(6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium hexamethyldisilazane / tetrahydrofuran / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / ethanol / 4 h / 90 °C / Inert atmosphere

With sodium carbonate; lithium hexamethyldisilazane; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; ethanol;