5-Chloro-1-cyclopropyl-1,4-dihydro-6,7-bis[(4-methoxyphenyl)methoxy]-4-oxo-3-quinolinecarboxylic acid

Base Information

Chemical Name:5-Chloro-1-cyclopropyl-1,4-dihydro-6,7-bis[(4-methoxyphenyl)methoxy]-4-oxo-3-quinolinecarboxylic acid
CAS No.:1429440-05-0
Molecular Formula:C₂₉H₂₆ClNO₇
Molecular Weight:535.981
Hs Code.:
Mol file:1429440-05-0.mol

Synonyms:5-chloro-1-cyclopropyl-6,7-bis((4-methoxybenzyl)oxy)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Suppliers and Price of 5-Chloro-1-cyclopropyl-1,4-dihydro-6,7-bis[(4-methoxyphenyl)methoxy]-4-oxo-3-quinolinecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-Chloro-1-cyclopropyl-6,7-bis((4-methoxybenzyl)oxy)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 95+%
250mg
$ 359.00

Crysdot
5-Chloro-1-cyclopropyl-6,7-bis((4-methoxybenzyl)oxy)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 95+%
1g
$ 897.00

Chemenu
5-Chloro-1-cyclopropyl-6,7-bis((4-methoxybenzyl)oxy)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 95%
1g
$ 839.00

Alichem
5-Chloro-1-cyclopropyl-6,7-bis((4-methoxybenzyl)oxy)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid
1g
$ 729.22

Total 6 raw suppliers

Chemical Property of 5-Chloro-1-cyclopropyl-1,4-dihydro-6,7-bis[(4-methoxyphenyl)methoxy]-4-oxo-3-quinolinecarboxylic acid

Chemical Property:

Boiling Point:748.3±60.0 °C(Predicted)
PKA:6.38±0.50(Predicted)
Density:1.397±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

5-Chloro-1-cyclopropyl-6,7-bis((4-methoxybenzyl)oxy)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-Chloro-1-cyclopropyl-1,4-dihydro-6,7-bis[(4-methoxyphenyl)methoxy]-4-oxo-3-quinolinecarboxylic acid

There total 9 articles about 5-Chloro-1-cyclopropyl-1,4-dihydro-6,7-bis[(4-methoxyphenyl)methoxy]-4-oxo-3-quinolinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1429440-04-9
4-methoxybenzyl 5-chloro-1-cyclopropyl-6,7-bis((4-methoxybenzyl)oxy)-4-oxo-1,4-dihydroquinolin-3-carboxylate

: 1429440-05-0
5-chloro-1-cyclopropyl-6,7-bis((4-methoxybenzyl)oxy)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Guidance literature:: With water; potassium hydroxide; In methanol; at 90 ℃; for 3h; Inert atmosphere;

Reference yield:

: 138998-46-6
ethyl 3-(dimethylamino)-2-(2,4,5-trifluorobenzoyl)prop-2-enoate

: 1429440-05-0
5-chloro-1-cyclopropyl-6,7-bis((4-methoxybenzyl)oxy)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Guidance literature:: Multi-step reaction with 8 steps

1.1: diethyl ether; ethanol / 2 h / 20 °C / Inert atmosphere

1.2: 2 h / 100 °C / Inert atmosphere

2.1: water; potassium hydroxide / 48 h / 130 °C / Inert atmosphere

3.1: sulfuric acid; potassium nitrate / 0 - 20 °C / Inert atmosphere

4.1: sodiumsulfide nonahydrate; water / ethanol / 2 h / 100 °C / Inert atmosphere

5.1: hydrogenchloride; sodium nitrite / water / 7 h / 0 - 95 °C / Inert atmosphere

6.1: methanol; boron tribromide / dichloromethane / -78 - 20 °C / Inert atmosphere

7.1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 50 °C / Inert atmosphere

8.1: water; potassium hydroxide / methanol / 3 h / 90 °C / Inert atmosphere

With hydrogenchloride; methanol; sodiumsulfide nonahydrate; sulfuric acid; water; boron tribromide; potassium carbonate; potassium nitrate; potassium hydroxide; sodium nitrite; In methanol; diethyl ether; ethanol; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

: 98349-25-8
ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylate

: 1429440-05-0
5-chloro-1-cyclopropyl-6,7-bis((4-methoxybenzyl)oxy)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Guidance literature:: Multi-step reaction with 7 steps

1: water; potassium hydroxide / 48 h / 130 °C / Inert atmosphere

2: sulfuric acid; potassium nitrate / 0 - 20 °C / Inert atmosphere

3: sodiumsulfide nonahydrate; water / ethanol / 2 h / 100 °C / Inert atmosphere

4: hydrogenchloride; sodium nitrite / water / 7 h / 0 - 95 °C / Inert atmosphere

5: methanol; boron tribromide / dichloromethane / -78 - 20 °C / Inert atmosphere

6: potassium carbonate / N,N-dimethyl-formamide / 5 h / 50 °C / Inert atmosphere

7: water; potassium hydroxide / methanol / 3 h / 90 °C / Inert atmosphere

With hydrogenchloride; methanol; sodiumsulfide nonahydrate; sulfuric acid; water; boron tribromide; potassium carbonate; potassium nitrate; potassium hydroxide; sodium nitrite; In methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide;