Ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate

Base Information

Chemical Name:Ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate
CAS No.:98349-25-8
Molecular Formula:C15H13F2NO3
Molecular Weight:293.27
Hs Code.:2933499090
European Community (EC) Number:422-380-0
DSSTox Substance ID:DTXSID50431269
Nikkaji Number:J1.824.783F
Wikidata:Q82245118
Mol file:98349-25-8.mol

Synonyms:98349-25-8;ETHYL 1-CYCLOPROPYL-6,7-DIFLUORO-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLATE;ethyl 1-cyclopropyl-6,7-difluoro-4-oxoquinoline-3-carboxylate;ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate;MFCD01646378;EC 422-380-0;SCHEMBL4306583;C15H13F2NO3;DTXSID50431269;BCP13372;CL1050;SB71654;DS-11689;SY046721;CS-0151710;E1181;A917075;ethyl 1-cyclopropyl-1,4-dihydro-6,7-difluoro-4-oxo-quinoline-3-carboxylate;ethyl 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinoline-carboxylate;ethyl 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate;ethyl 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate;1-cyclopropyl-6,7-difluoro- 1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, ethyl ester;1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, ethyl ester;1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester;ETHYL1-CYCLOPROPYL-6,7-DIFLUORO-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLATE

Suppliers and Price of Ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate
100mg
$ 1320.00

Crysdot
Ethyl1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 95+%
25g
$ 322.00

Crysdot
Ethyl1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 95+%
100g
$ 812.00

Chemenu
ethyl1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 95%
100g
$ 767.00

Chemenu
ethyl1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 95%
5g
$ 112.00

Ambeed
Ethyl1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 97%
1g
$ 34.00

Ambeed
Ethyl1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 97%
250mg
$ 15.00

Ambeed
Ethyl1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 97%
10g
$ 178.00

Ambeed
Ethyl1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 97%
5g
$ 114.00

Ambeed
Ethyl1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 97%
25g
$ 338.00

Total 25 raw suppliers

Chemical Property of Ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate

Chemical Property:

Melting Point:229-230℃ (ethyl acetate )
PSA：48.30000
LogP:2.79130
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:293.08634960
Heavy Atom Count:21
Complexity:489

Purity/Quality:

99.9% ^*data from raw suppliers

Ethyl1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CN(C2=CC(=C(C=C2C1=O)F)F)C3CC3
Uses Ethyl 1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate is an derivative of gatifloxacin (G250000), an antibacterial agent. Ethyl 1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydro-3-quin olinecarboxylate was shown biological activities against Mycobacterium leprae and tubercluosis. Ethyl 1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate is an derivative of gatifloxacin (G250000), an antibacterial agent. Ethyl 1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate was shown biological activities against Mycobacterium leprae and tubercluosis.

Technology Process of Ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate

There total 23 articles about Ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.7%

: 2-chloro-α-[(cyclopropylamino)methylene]-4,5-difluoro-β-oxobenzenepropanoic acid, ethyl ester

: 98349-25-8
ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylate

Guidance literature:: With potassium phosphate; In acetonitrile; at 75 - 80 ℃; for 2h;

Reference yield: 97.0%

: 138998-46-6
ethyl 3-(dimethylamino)-2-(2,4,5-trifluorobenzoyl)prop-2-enoate

: 765-30-0
Cyclopropylamine

: 98349-25-8
ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylate

Guidance literature:: ethyl 3-(dimethylamino)-2-(2,4,5-trifluorobenzoyl)prop-2-enoate; Cyclopropylamine; In diethyl ether; ethanol; at 20 ℃; for 2h; Inert atmosphere;

With potassium carbonate; In diethyl ether; ethanol; N,N-dimethyl-formamide; at 100 ℃; for 2h; Inert atmosphere;