Technology Process of C20H19NO5
There total 4 articles about C20H19NO5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-oxo-propionic acid ethyl ester;
With
bromine;
In
1,2-dimethoxyethane;
at 60 ℃;
for 1h;
3-benzyloxy-4-methoxybenzamide;
In
1,2-dimethoxyethane;
for 8h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: thionyl chloride / 2 h / Reflux
2.1: tetrabutyl-ammonium chloride; potassium carbonate / water; toluene / 2 h / 80 °C
2.2: 2 h / Reflux
3.1: thionyl chloride; 1-methyl-pyrrolidin-2-one / toluene / 3 h / 20 °C
4.1: ammonium hydroxide / water; toluene; 1-methyl-pyrrolidin-2-one / Cooling with ice
5.1: bromine / 1,2-dimethoxyethane / 1 h / 60 °C
5.2: 8 h / Reflux
With
1-methyl-pyrrolidin-2-one; ammonium hydroxide; thionyl chloride; tetrabutyl-ammonium chloride; bromine; potassium carbonate;
In
1-methyl-pyrrolidin-2-one; 1,2-dimethoxyethane; water; toluene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: tetrabutyl-ammonium chloride; potassium carbonate / water; toluene / 2 h / 80 °C
1.2: 2 h / Reflux
2.1: thionyl chloride; 1-methyl-pyrrolidin-2-one / toluene / 3 h / 20 °C
3.1: ammonium hydroxide / water; toluene; 1-methyl-pyrrolidin-2-one / Cooling with ice
4.1: bromine / 1,2-dimethoxyethane / 1 h / 60 °C
4.2: 8 h / Reflux
With
1-methyl-pyrrolidin-2-one; ammonium hydroxide; thionyl chloride; tetrabutyl-ammonium chloride; bromine; potassium carbonate;
In
1-methyl-pyrrolidin-2-one; 1,2-dimethoxyethane; water; toluene;
