25,27-bis[(p-nitrophenyl)sulfonyloxy]-26,28-dipropoxy-calix[4]-arene

Base Information

• Chemical Name: 25,27-bis[(p-nitrophenyl)sulfonyloxy]-26,28-dipropoxy-calix[4]-arene
• CAS No.: 1314582-83-6
• Molecular Formula: C₄₆H₄₂N₂O₁₂S₂
• Molecular Weight: 878.978
• Mol file: 1314582-83-6.mol

Synonyms:25,27-bis[(p-nitrophenyl)sulfonyloxy]-26,28-dipropoxy-calix[4]-arene

Chemical Property of 25,27-bis[(p-nitrophenyl)sulfonyloxy]-26,28-dipropoxy-calix[4]-arene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 25,27-bis[(p-nitrophenyl)sulfonyloxy]-26,28-dipropoxy-calix[4]-arene

There total 3 articles about 25,27-bis[(p-nitrophenyl)sulfonyloxy]-26,28-dipropoxy-calix[4]-arene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

25,27-dihydroxy-26,28-dipropoxycalix[4]arene (143406-35-3,162301-48-6) + 4-Nitrobenzenesulfonyl chloride (98-74-8) → 25,27-bis[(p-nitrophenyl)sulfonyloxy]-26,28-dipropoxy-calix[4]-arene (1314582-83-6)

Guidance literature:

25,27-dihydroxy-26,28-dipropoxycalix[4]arene; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.5h;

4-Nitrobenzenesulfonyl chloride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 168h;

DOI:10.1016/j.tet.2011.05.049

Reference yield:

5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene (157432-87-6,288302-11-4,288302-12-5,60705-62-6) → 25,27-bis[(p-nitrophenyl)sulfonyloxy]-26,28-dipropoxy-calix[4]-arene (1314582-83-6)

Guidance literature:

Multi-step reaction with 3 steps

1: phenol; aluminum (III) chloride / toluene / Inert atmosphere

2: potassium carbonate / acetonitrile / Inert atmosphere

3: sodium hydride / N,N-dimethyl-formamide / Inert atmosphere

With aluminum (III) chloride; sodium hydride; potassium carbonate; phenol; In N,N-dimethyl-formamide; toluene; acetonitrile;

DOI:10.1002/ejoc.202100676

Reference yield:

25,26,27,28-tetrakis(hydroxy)calix[4]arene (248590-47-8,74568-07-3) → 25,27-bis[(p-nitrophenyl)sulfonyloxy]-26,28-dipropoxy-calix[4]-arene (1314582-83-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / Inert atmosphere

2: sodium hydride / N,N-dimethyl-formamide / Inert atmosphere

With sodium hydride; potassium carbonate; In N,N-dimethyl-formamide; acetonitrile;

DOI:10.1002/ejoc.202100676

upstream raw materials:

25,27-dihydroxy-26,28-dipropoxycalix[4]arene

4-Nitrobenzenesulfonyl chloride

5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene

25,26,27,28-tetrakis(hydroxy)calix[4]arene

Downstream raw materials:

5,17-bis(N'-phenylureido)-26,28-dipropoxycalix[4]arene-25,27-diol

5,17-dinitro-25,27-bis(p-nitrobenzenesulfonyloxy)-26,28-dipropoxycalix[4]arene

5-nitro-25,27-bis(p-nitrobenzenesulfonyloxy)-26,28-dipropoxycalix[4]arene

5,17-diformyl-25,27-bis(p-nitrobenzenesulfonyloxy)-26,28-dipropoxycalix[4]arene