3,4-dimethylphenyl-4'-methoxyphenylamine

Base Information

• Chemical Name: 3,4-dimethylphenyl-4'-methoxyphenylamine
• CAS No.: 198291-18-8
• Molecular Formula: C₁₅H₁₇NO
• Molecular Weight: 227.306
• Mol file: 198291-18-8.mol

Synonyms:3,4-dimethylphenyl-4'-methoxyphenylamine

Chemical Property of 3,4-dimethylphenyl-4'-methoxyphenylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4-dimethylphenyl-4'-methoxyphenylamine

There total 6 articles about 3,4-dimethylphenyl-4'-methoxyphenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-chloro-1,2-dimethylbenzene (615-60-1) + 4-methoxy-aniline (104-94-9) → 3,4-dimethylphenyl-4'-methoxyphenylamine (198291-18-8)

Guidance literature:

With potassium tert-butylate; In 1,4-dioxane; at 100 ℃; for 20h;

DOI:10.1039/d1cy00669j

Reference yield: 67.0%

1-bromo-4-methoxy-benzene (104-92-7) + 4-amino-o-xylene (95-64-7) → 3,4-dimethylphenyl-4'-methoxyphenylamine (198291-18-8)

Guidance literature:

With tri-tert-butyl phosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; sodium t-butanolate; In toluene; for 2h; Inert atmosphere; Reflux;

DOI:10.1021/jo2020906

Reference yield:

tris(4-methoxyphenyl)bismuth (33397-21-6) + 4-amino-o-xylene (95-64-7) → 3,4-dimethylphenyl-4'-methoxyphenylamine (198291-18-8)

Guidance literature:

With copper diacetate; [bis(acetoxy)iodo]benzene; Yield given. Multistep reaction; 1.) CH₂Cl₂, room temp., 17 h, 2.) CH₂Cl₂, room temp., 2 h;

DOI:10.1016/S0040-4020(98)00126-4

upstream raw materials:

tris(4-methoxyphenyl)bismuth

4-amino-o-xylene

1-bromo-4-methoxy-benzene

N-(3,4-dimethylphenyl)-4-methylbenzenesulfonamide

Downstream raw materials:

C₄₂H₄₀N₂O₂

C₆₃H₆₀N₄O₃

C₅₀H₆₄N₂O₄Si₄

N-(3,4-dimethylphenyl)-N-(4-methoxyphenyl)-[1,1'-biphenyl]-4-amine