Methyl 4,5-dibromo-3-methoxythiophene-2-carboxylate

Base Information

Chemical Name:Methyl 4,5-dibromo-3-methoxythiophene-2-carboxylate
CAS No.:175137-42-5
Molecular Formula:C7H6 Br2 O3 S
Molecular Weight:329.997
Hs Code.:2934999090
DSSTox Substance ID:DTXSID00384574
Wikidata:Q82176809
Mol file:175137-42-5.mol

Synonyms:methyl 4,5-dibromo-3-methoxythiophene-2-carboxylate;175137-42-5;Maybridge3_001410;SCHEMBL2682770;DTXSID00384574;HMS1435A02;IDI1_012797;CS-0243928;FT-0769202;EN300-269832

Suppliers and Price of Methyl 4,5-dibromo-3-methoxythiophene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl4,5-dibromo-3-methoxythiophene-2-carboxylate 95+%
10g
$ 1935.00

Crysdot
Methyl4,5-dibromo-3-methoxythiophene-2-carboxylate 95+%
5g
$ 1439.00

Crysdot
Methyl4,5-dibromo-3-methoxythiophene-2-carboxylate 95+%
1g
$ 644.00

Arctom
Methyl4,5-dibromo-3-methoxythiophene-2-carboxylate 95%
1g
$ 644.00

Total 6 raw suppliers

Chemical Property of Methyl 4,5-dibromo-3-methoxythiophene-2-carboxylate

Chemical Property:

PSA：63.77000
LogP:3.06830
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:329.83839
Heavy Atom Count:13
Complexity:202

Purity/Quality:

97% ^*data from raw suppliers

Methyl4,5-dibromo-3-methoxythiophene-2-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(SC(=C1Br)Br)C(=O)OC

Technology Process of Methyl 4,5-dibromo-3-methoxythiophene-2-carboxylate

There total 1 articles about Methyl 4,5-dibromo-3-methoxythiophene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 96232-71-2
4,5-dibromo-3-hydroxythiophene-2-carboxylic acid methyl ester

: 74-88-4
methyl iodide

: 175137-42-5
Methyl 4,5-dibromo-3-methoxythiophene-2-carboxylate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

Reference yield:

: 175137-42-5
Methyl 4,5-dibromo-3-methoxythiophene-2-carboxylate

: 3900-89-8
2-Chlorobenzeneboronic acid

: 1246405-84-4
methyl 4-bromo-5-(2-chlorophenyl)-3-methoxythiophene-2-carboxylate

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 110 ℃; Inert atmosphere;

Reference yield:

: 175137-42-5
Methyl 4,5-dibromo-3-methoxythiophene-2-carboxylate

: 1246405-85-5
4-(4-Chlorophenyl)-5-(2,4-dichlorophenyl)-3-methoxythiophene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 18 h / 110 °C / Inert atmosphere

2.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 18 h / 110 °C / Inert atmosphere

3.1: sodium hydroxide; methanol / N,N-dimethyl-formamide / 18 h / 80 °C

3.2: pH 2

With methanol; sodium carbonate; sodium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; toluene;