Benzeneacetonitrile, 4-nitro-, radical ion(2-) (9CI)

Base Information

• Chemical Name: Benzeneacetonitrile, 4-nitro-, radical ion(2-) (9CI)
• CAS No.: 174848-08-9
• Molecular Formula: C₈H₆N₂O₂
• Molecular Weight: 162.148
• Mol file: 174848-08-9.mol

Synonyms:Benzeneacetonitrile, 4-nitro-, radical ion(2-) (9CI)

Chemical Property of Benzeneacetonitrile, 4-nitro-, radical ion(2-) (9CI)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzeneacetonitrile, 4-nitro-, radical ion(2-) (9CI)

There total 61 articles about Benzeneacetonitrile, 4-nitro-, radical ion(2-) (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

tetra-n-butylammonium cyanide (10442-39-4) + 1-((methoxymethoxy)methyl)-4-nitrobenzene (139884-17-6) → 4-Nitrophenylacetonitrile (555-21-5,34512-13-5,174848-08-9)

Guidance literature:

With 1-(n-butyl)-3-methylimidazolium tetrachloroindate; at 135 - 140 ℃; for 0.0333333h; chemoselective reaction; Microwave irradiation; Neat (no solvent);

DOI:10.1016/j.tetlet.2010.04.056

Reference yield: 88.0%

phenylacetonitrile (140-29-4) → 4-Nitrophenylacetonitrile (555-21-5,34512-13-5,174848-08-9)

Guidance literature:

With sulfuric acid; nitric acid; at 10 - 20 ℃; for 1h;

DOI:10.1016/j.bioorg.2020.103977

Reference yield: 76.0%

4-iodophenylacetonitrile (51628-12-7) → 4-Nitrophenylacetonitrile (555-21-5,34512-13-5,174848-08-9)

Guidance literature:

With 1,10-Phenanthroline; iron(II) sulfate; potassium nitrate; In dimethyl sulfoxide; at 20 ℃; for 48h; UV-irradiation; Inert atmosphere;

DOI:10.1021/acscatal.1c02272

upstream raw materials:

phenylacetonitrile

methanol

p-nitro-phenyl-acetonitrile

2-(4-nitrophenyl)-3-phenylacrylonitrile

Downstream raw materials:

3-(3-nitro-phenyl)-2-(4-nitro-phenyl)-acrylonitrile

3-hydroxy-3-(3-nitro-phenyl)-2-(4-nitro-phenyl)-propionitrile

3c-(5-bromo-[2]thienyl)-2-(4-nitro-phenyl)-acrylonitrile

1-(2-methyl-indol-3-yl)-2-(4-nitro-phenyl)-ethanone