(E)-(2R,3S)-3-Methoxy-2-methyl-5-phenyl-pent-4-enethioic acid S-ethyl ester

Base Information

Chemical Name:(E)-(2R,3S)-3-Methoxy-2-methyl-5-phenyl-pent-4-enethioic acid S-ethyl ester
CAS No.:478011-20-0
Molecular Formula:C₁₅H₂₀O₂S
Molecular Weight:264.389
Hs Code.:

Synonyms:(E)-(2R,3S)-3-Methoxy-2-methyl-5-phenyl-pent-4-enethioic acid S-ethyl ester

Suppliers and Price of (E)-(2R,3S)-3-Methoxy-2-methyl-5-phenyl-pent-4-enethioic acid S-ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-(2R,3S)-3-Methoxy-2-methyl-5-phenyl-pent-4-enethioic acid S-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-(2R,3S)-3-Methoxy-2-methyl-5-phenyl-pent-4-enethioic acid S-ethyl ester

There total 3 articles about (E)-(2R,3S)-3-Methoxy-2-methyl-5-phenyl-pent-4-enethioic acid S-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 173377-13-4
(E)-(2R,3S)-3-Hydroxy-2-methyl-5-phenyl-pent-4-enethioic acid S-ethyl ester

: 478011-20-0
(E)-(2R,3S)-3-Methoxy-2-methyl-5-phenyl-pent-4-enethioic acid S-ethyl ester

Guidance literature:: With boron trifluoride diethyl etherate; In diethyl ether; at 0 - 20 ℃; for 1h;
DOI:10.1016/S0960-894X(02)00625-X

Reference yield:

: 63584-42-9,130535-66-9,63584-50-9
(Z)-1-ethylthio-1-(trimethylsiloxy)propene

: 478011-20-0
(E)-(2R,3S)-3-Methoxy-2-methyl-5-phenyl-pent-4-enethioic acid S-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / Sn(OTf)2; n-Bu2Sn(OAc)2; (R)-2-(α-naphthylaminomethyl)-N-methylpyrrolidine / CH2Cl2 / 3 h / -78 °C

2: 78 percent / BF₃*OEt₂ / diethyl ether / 1 h / 0 - 20 °C

With tin(II) trifluoromethanesulfonate; N-(((R)-1-methylpyrrolidin-2-yl)methyl)naphthalen-1-amine; boron trifluoride diethyl etherate; dibutyltin diacetate; In diethyl ether; dichloromethane; 1: Mukaiyama's asymmetric aldol reaction;
DOI:10.1016/S0960-894X(02)00625-X

Reference yield:

: 104-55-2
3-phenyl-propenal

: 478011-20-0
(E)-(2R,3S)-3-Methoxy-2-methyl-5-phenyl-pent-4-enethioic acid S-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / Sn(OTf)2; n-Bu2Sn(OAc)2; (R)-2-(α-naphthylaminomethyl)-N-methylpyrrolidine / CH2Cl2 / 3 h / -78 °C

2: 78 percent / BF₃*OEt₂ / diethyl ether / 1 h / 0 - 20 °C

With tin(II) trifluoromethanesulfonate; N-(((R)-1-methylpyrrolidin-2-yl)methyl)naphthalen-1-amine; boron trifluoride diethyl etherate; dibutyltin diacetate; In diethyl ether; dichloromethane; 1: Mukaiyama's asymmetric aldol reaction;
DOI:10.1016/S0960-894X(02)00625-X